CTNNAL1 (catenin alpha like 1)

2003-02-01 Affiliation

Identity

HGNC

CTNNAL1

LOCATION

9q31.3

LOCUSID

8727

ALIAS

ACRP,CLLP,alpha-CATU

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 8727
MIM: 604785
HGNC: 2512
Ensembl: ENSG00000119326

Variants:

dbSNP: 8727
ClinVar: 8727
TCGA: ENSG00000119326
COSMIC: CTNNAL1

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000119326	ENST00000325551	Q9UBT7
ENSG00000119326	ENST00000374593	Q5JTQ6
ENSG00000119326	ENST00000374594	Q5JTQ9
ENSG00000119326	ENST00000374595	Q9UBT7

Expression (GTEx)

100

150

200

250

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

References

Pubmed ID	Year	Title	Citations
37715489	2023	CTNNAL1 deficiency suppresses CFTR expression in HDM-induced asthma mouse model through ROCK1-CAL signaling pathway.	1
37715489	2023	CTNNAL1 deficiency suppresses CFTR expression in HDM-induced asthma mouse model through ROCK1-CAL signaling pathway.	1
35154481	2022	α-Catulin promotes cancer stemness by antagonizing WWP1-mediated KLF5 degradation in lung cancer.	9
35154481	2022	α-Catulin promotes cancer stemness by antagonizing WWP1-mediated KLF5 degradation in lung cancer.	9
32139661	2020	Genetic variants in RET, ARHGEF3 and CTNNAL1, and relevant interaction networks, contribute to the risk of Hirschsprung disease.	4
32139661	2020	Genetic variants in RET, ARHGEF3 and CTNNAL1, and relevant interaction networks, contribute to the risk of Hirschsprung disease.	4
29791759	2018	CTNNAL1 inhibits ozone-induced epithelial-mesenchymal transition in human bronchial epithelial cells.	10
29791759	2018	CTNNAL1 inhibits ozone-induced epithelial-mesenchymal transition in human bronchial epithelial cells.	10
26311049	2016	The upregulated α-catulin expression was involved in head-neck squamous cell carcinogenesis by promoting proliferation, migration, invasion, and epithelial to mesenchymal transition.	3
26311049	2016	The upregulated α-catulin expression was involved in head-neck squamous cell carcinogenesis by promoting proliferation, migration, invasion, and epithelial to mesenchymal transition.	3
25793618	2015	Alpha-catulin contributes to drug-resistance of melanoma by activating NF-κB and AP-1.	14
25793618	2015	Alpha-catulin contributes to drug-resistance of melanoma by activating NF-κB and AP-1.	14
22733455	2013	α-Catulin downregulates E-cadherin and promotes melanoma progression and invasion.	21
23047866	2013	α-Catulin drives metastasis by activating ILK and driving an αvβ3 integrin signaling axis.	21
22733455	2013	α-Catulin downregulates E-cadherin and promotes melanoma progression and invasion.	21

Citation

Dessen P

CTNNAL1 (catenin alpha like 1)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/40194/ctnnal1-(catenin-alpha-like-1)