Identity
HGNC
LOCATION
4q13.3
LOCUSID
ALIAS
CINC-2a,GRO2,GROb,MGSA-b,MIP-2a,MIP2,MIP2A,SCYB2
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 2920
MIM: 139110
HGNC: 4603
Ensembl: ENSG00000081041
Variants:
dbSNP: 2920
ClinVar: 2920
TCGA: ENSG00000081041
COSMIC: CXCL2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000081041 | ENST00000508487 | P19875 |
| ENSG00000081041 | ENST00000508487 | A0A024RDD9 |
Expression (GTEx)
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36577281 | 2023 | Tumor-associated macrophages mediate gastrointestinal stromal tumor cell metastasis through CXCL2/CXCR2. | 6 |
| 36577281 | 2023 | Tumor-associated macrophages mediate gastrointestinal stromal tumor cell metastasis through CXCL2/CXCR2. | 6 |
| 35541899 | 2022 | SNAIL Induces EMT and Lung Metastasis of Tumours Secreting CXCL2 to Promote the Invasion of M2-Type Immunosuppressed Macrophages in Colorectal Cancer. | 23 |
| 36073801 | 2022 | ARG1 and CXCL2 are potential biomarkers target for psoriasis patients. | 0 |
| 36281171 | 2022 | CXCL2 acts as a prognostic biomarker and associated with immune infiltrates in stomach adenocarcinoma. | 1 |
| 35541899 | 2022 | SNAIL Induces EMT and Lung Metastasis of Tumours Secreting CXCL2 to Promote the Invasion of M2-Type Immunosuppressed Macrophages in Colorectal Cancer. | 23 |
| 36073801 | 2022 | ARG1 and CXCL2 are potential biomarkers target for psoriasis patients. | 0 |
| 36281171 | 2022 | CXCL2 acts as a prognostic biomarker and associated with immune infiltrates in stomach adenocarcinoma. | 1 |
| 32988253 | 2021 | Identification of genes and miRNAs in paclitaxel treatment for breast cancer. | 4 |
| 33010041 | 2021 | Increased expression of CXCL2 in ACPA-positive rheumatoid arthritis and its role in osteoclastogenesis. | 11 |
| 33571109 | 2021 | Regulation of tumor immune suppression and cancer cell survival by CXCL1/2 elevation in glioblastoma multiforme. | 43 |
| 33793061 | 2021 | CXCL2 benefits acute myeloid leukemia cells in hypoxia. | 6 |
| 33807899 | 2021 | The CXCL2/IL8/CXCR2 Pathway Is Relevant for Brain Tumor Malignancy and Endothelial Cell Function. | 24 |
| 34085699 | 2021 | CXCL2/10/12/14 are prognostic biomarkers and correlated with immune infiltration in hepatocellular carcinoma. | 19 |
| 34115261 | 2021 | CXCL2-CXCR2 axis mediates αV integrin-dependent peritoneal metastasis of colon cancer cells. | 16 |
Citation
Dessen P
CXCL2 (C-X-C motif chemokine ligand 2)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/40221/cxcl2-(c-x-c-motif-chemokine-ligand-2)
