DAP3 (death associated protein 3)

2003-02-01  

Identity

HGNC
LOCATION
1q22
LOCUSID
ALIAS
DAP-3,MRP-S29,MRPS29,S29mt,bMRP-10
FUSION GENES

Other Information

Locus ID:

NCBI: 7818
MIM: 602074
HGNC: 2673
Ensembl: ENSG00000132676

Variants:

dbSNP: 7818
ClinVar: 7818
TCGA: ENSG00000132676
COSMIC: DAP3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000132676ENST00000343043P51398
ENSG00000132676ENST00000368336P51398
ENSG00000132676ENST00000421487P51398
ENSG00000132676ENST00000463295V9GZ61
ENSG00000132676ENST00000463575V9GY11
ENSG00000132676ENST00000465375V9GYL4
ENSG00000132676ENST00000470830V9GYJ3
ENSG00000132676ENST00000471214V9GYL9
ENSG00000132676ENST00000471642P51398
ENSG00000132676ENST00000475056V9GYC9
ENSG00000132676ENST00000477394V9GYA7
ENSG00000132676ENST00000479151V9GZ03
ENSG00000132676ENST00000490249V9GYW1
ENSG00000132676ENST00000491777V9GYF7
ENSG00000132676ENST00000497826V9GYJ9
ENSG00000132676ENST00000535183P51398
ENSG00000132676ENST00000608852V9GYR8

Expression (GTEx)

0
10
20
30
40
50
60
70
80

Pathways

PathwaySourceExternal ID
Organelle biogenesis and maintenanceREACTOMER-HSA-1852241
Mitochondrial translationREACTOMER-HSA-5368287
Mitochondrial translation initiationREACTOMER-HSA-5368286
Mitochondrial translation elongationREACTOMER-HSA-5389840
Mitochondrial translation terminationREACTOMER-HSA-5419276

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
190645712008Polymorphisms in mitochondrial genes and prostate cancer risk.20
151753412004Death-associated protein 3 localizes to the mitochondria and is involved in the process of mitochondrial fragmentation during cell death.19
182274312008Identification of phosphorylation sites in mammalian mitochondrial ribosomal protein DAP3.17
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.17
153028712004Functional role of death-associated protein 3 (DAP3) in anoikis.16
191036042009hNOA1 interacts with complex I and DAP3 and regulates mitochondrial respiration and apoptosis.16
196445112009IPS-1 is crucial for DAP3-mediated anoikis induction by caspase-8 activation.14
176135362007Tiling resolution array comparative genomic hybridization, expression and methylation analyses of dup(1q) in Burkitt lymphomas and pediatric high hyperdiploid acute lymphoblastic leukemias reveal clustered near-centromeric breakpoints and overexpression of genes in 1q22-32.3.12
263060392015Death-associated Protein 3 Regulates Mitochondrial-encoded Protein Synthesis and Mitochondrial Dynamics.9
195360942009Death-associated protein 3 is overexpressed in human thyroid oncocytic tumours.8

Citation

Dessen P

DAP3 (death associated protein 3)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/40262/dap3-(death-associated-protein-3)