PSRC1 (proline and serine rich coiled-coil 1)

2003-02-01  

Identity

HGNC
PSRC1
LOCATION
1p13.3
LOCUSID
84722
ALIAS
DDA3,FP3214
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 84722
MIM: 613126
HGNC: 24472
Ensembl: ENSG00000134222

Variants:

dbSNP: 84722
ClinVar: 84722
TCGA: ENSG00000134222
COSMIC: PSRC1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000134222ENST00000369903Q6PGN9
ENSG00000134222ENST00000369903A0A024R099
ENSG00000134222ENST00000369904Q6PGN9
ENSG00000134222ENST00000369907Q6PGN9
ENSG00000134222ENST00000369907A0A024R099
ENSG00000134222ENST00000369909Q6PGN9
ENSG00000134222ENST00000369909A0A024R099
ENSG00000134222ENST00000409138Q6PGN9
ENSG00000134222ENST00000409267Q6PGN9
ENSG00000134222ENST00000409267A0A024R099
ENSG00000134222ENST00000418914Q5T2Z0
ENSG00000134222ENST00000429031Q5T2Z1
ENSG00000134222ENST00000474126S4R3S8

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
100
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
327896892021Reciprocal regulation of Aurora kinase A and ATIP3 in the control of metaphase spindle length.6
327896892021Reciprocal regulation of Aurora kinase A and ATIP3 in the control of metaphase spindle length.6
326209982020Genetically programmed changes in transcription of the novel progranulin regulator.1
328588142020Association of the PSRC1 rs599839 Variant with Coronary Artery Disease in a Mexican Population.2
326209982020Genetically programmed changes in transcription of the novel progranulin regulator.1
328588142020Association of the PSRC1 rs599839 Variant with Coronary Artery Disease in a Mexican Population.2
297141252018Multivariate analysis for coronary heart disease in heterozygote familial hypercholesterolemia patients.2
297141252018Multivariate analysis for coronary heart disease in heterozygote familial hypercholesterolemia patients.2
267972782016Ska1 cooperates with DDA3 for spindle dynamics and spindle attachment to kinetochore.3
268205362016ANKRD53 interacts with DDA3 and regulates chromosome integrity during mitosis.5
272840042016DDA3 and Mdp3 modulate Kif2a recruitment onto the mitotic spindle to control minus-end spindle dynamics.9
276979242016ASB7 regulates spindle dynamics and genome integrity by targeting DDA3 for proteasomal degradation.13
267972782016Ska1 cooperates with DDA3 for spindle dynamics and spindle attachment to kinetochore.3
268205362016ANKRD53 interacts with DDA3 and regulates chromosome integrity during mitosis.5
272840042016DDA3 and Mdp3 modulate Kif2a recruitment onto the mitotic spindle to control minus-end spindle dynamics.9

Citation

Dessen P

PSRC1 (proline and serine rich coiled-coil 1)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/40277/psrc1-(proline-and-serine-rich-coiled-coil-1)