DDX49 (DEAD-box helicase 49)

2003-12-01  

Identity

HGNC
LOCATION
19p13.11
LOCUSID
ALIAS
Dbp8,R27090_2
FUSION GENES

Other Information

Locus ID:

NCBI: 54555
HGNC: 18684
Ensembl: ENSG00000105671

Variants:

dbSNP: 54555
ClinVar: 54555
TCGA: ENSG00000105671
COSMIC: DDX49

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000105671ENST00000247003Q9Y6V7
ENSG00000105671ENST00000593361M0QXD4
ENSG00000105671ENST00000594021M0QZC0
ENSG00000105671ENST00000595858M0R0K1
ENSG00000105671ENST00000598972M0R1S3
ENSG00000105671ENST00000602113M0QXD4
ENSG00000105671ENST00000629999M0R0K1

Expression (GTEx)

0
10
20
30
40
50
60
70

Pathways

PathwaySourceExternal ID
Gene ExpressionREACTOMER-HSA-74160
rRNA processingREACTOMER-HSA-72312
Major pathway of rRNA processing in the nucleolus and cytosolREACTOMER-HSA-6791226
rRNA modification in the nucleus and cytosolREACTOMER-HSA-6790901
rRNA processing in the nucleus and cytosolREACTOMER-HSA-8868773

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
296181222018DDX49 is an RNA helicase that affects translation by regulating mRNA export and the levels of pre-ribosomal RNA.3

Citation

Dessen P

DDX49 (DEAD-box helicase 49)

Atlas Genet Cytogenet Oncol Haematol. 2003-12-01

Online version: http://atlasgeneticsoncology.org/gene/40289/ddx49-(dead-box-helicase-49)