Identity
HGNC
LOCATION
1p32.3
LOCUSID
ALIAS
DCE,Nbla03646,SELADIN1,seladin-1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 1718
MIM: 606418
HGNC: 2859
Ensembl: ENSG00000116133
Variants:
dbSNP: 1718
ClinVar: 1718
TCGA: ENSG00000116133
COSMIC: DHCR24
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38407305 | 2024 | DHCR24 Insufficiency Promotes Vascular Endothelial Cell Senescence and Endothelial Dysfunction via Inhibition of Caveolin-1/ERK Signaling. | 0 |
| 38407305 | 2024 | DHCR24 Insufficiency Promotes Vascular Endothelial Cell Senescence and Endothelial Dysfunction via Inhibition of Caveolin-1/ERK Signaling. | 0 |
| 36946578 | 2023 | LncRNA ENST00000370438 promotes cell proliferation by upregulating DHCR24 in breast cancer. | 2 |
| 37011864 | 2023 | Cellular cholesterol loss by DHCR24 knockdown leads to Aβ production by changing APP intracellular localization. | 0 |
| 37458798 | 2023 | High fat diet induces brain injury and neuronal apoptosis via down-regulating 3-β hydroxycholesterol 24 reductase (DHCR24). | 3 |
| 36946578 | 2023 | LncRNA ENST00000370438 promotes cell proliferation by upregulating DHCR24 in breast cancer. | 2 |
| 37011864 | 2023 | Cellular cholesterol loss by DHCR24 knockdown leads to Aβ production by changing APP intracellular localization. | 0 |
| 37458798 | 2023 | High fat diet induces brain injury and neuronal apoptosis via down-regulating 3-β hydroxycholesterol 24 reductase (DHCR24). | 3 |
| 34624089 | 2022 | Oncogenic role of the SOX9-DHCR24-cholesterol biosynthesis axis in IGH-BCL2+ diffuse large B-cell lymphomas. | 12 |
| 34949154 | 2022 | 24-Dehydrocholesterol Reductase alleviates oxidative damage-induced apoptosis in alveolar epithelial cells via regulating Phosphatidylinositol-3-Kinase/Protein Kinase B activation. | 4 |
| 35296367 | 2022 | The role of DHCR24 in the pathogenesis of AD: re-cognition of the relationship between cholesterol and AD pathogenesis. | 13 |
| 36068004 | 2022 | Hsa_circ_0003221 facilitates the malignant development of bladder cancer cells via resulting in the upregulation of DHCR24 by targeting miR-892b. | 3 |
| 36483599 | 2022 | Anticancer peptide Q7 suppresses the growth and migration of human endometrial cancer by inhibiting DHCR24 expression and modulating the AKT-mediated pathway. | 2 |
| 34624089 | 2022 | Oncogenic role of the SOX9-DHCR24-cholesterol biosynthesis axis in IGH-BCL2+ diffuse large B-cell lymphomas. | 12 |
| 34949154 | 2022 | 24-Dehydrocholesterol Reductase alleviates oxidative damage-induced apoptosis in alveolar epithelial cells via regulating Phosphatidylinositol-3-Kinase/Protein Kinase B activation. | 4 |
Citation
Dessen P
DHCR24 (24-dehydrocholesterol reductase)
Atlas Genet Cytogenet Oncol Haematol. 2003-08-01
Online version: http://atlasgeneticsoncology.org/gene/40302/dhcr24-(24-dehydrocholesterol-reductase)
