DHX34 (DExH-box helicase 34)

2003-06-01  

Identity

HGNC
DHX34
LOCATION
19q13.32
LOCUSID
9704
ALIAS
DDX34,HRH1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 9704
MIM: 615475
HGNC: 16719
Ensembl: ENSG00000134815

Variants:

dbSNP: 9704
ClinVar: 9704
TCGA: ENSG00000134815
COSMIC: DHX34

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000134815ENST00000328771Q14147
ENSG00000134815ENST00000460681H7C504

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
N/A

References

Pubmed IDYearTitleCitations
357682792022A dual role for the RNA helicase DHX34 in NMD and pre-mRNA splicing and its function in hematopoietic differentiation.3
357682792022A dual role for the RNA helicase DHX34 in NMD and pre-mRNA splicing and its function in hematopoietic differentiation.3
332057502020Regulation of RUVBL1-RUVBL2 AAA-ATPases by the nonsense-mediated mRNA decay factor DHX34, as evidenced by Cryo-EM.7
332057502020Regulation of RUVBL1-RUVBL2 AAA-ATPases by the nonsense-mediated mRNA decay factor DHX34, as evidenced by Cryo-EM.7
312568772019Paralog Studies Augment Gene Discovery: DDX and DHX Genes.40
312568772019Paralog Studies Augment Gene Discovery: DDX and DHX Genes.40
268417012016The RNA helicase DHX34 functions as a scaffold for SMG1-mediated UPF1 phosphorylation.27
268417012016The RNA helicase DHX34 functions as a scaffold for SMG1-mediated UPF1 phosphorylation.27
252204602014The RNA helicase DHX34 activates NMD by promoting a transition from the surveillance to the decay-inducing complex.37
252204602014The RNA helicase DHX34 activates NMD by promoting a transition from the surveillance to the decay-inducing complex.37
238280422013DHX34 and NBAS form part of an autoregulatory NMD circuit that regulates endogenous RNA targets in human cells, zebrafish and Caenorhabditis elegans.52
238280422013DHX34 and NBAS form part of an autoregulatory NMD circuit that regulates endogenous RNA targets in human cells, zebrafish and Caenorhabditis elegans.52

Citation

Dessen P

DHX34 (DExH-box helicase 34)

Atlas Genet Cytogenet Oncol Haematol. 2003-06-01

Online version: http://atlasgeneticsoncology.org/gene/40305/dhx34-(dexh-box-helicase-34)