DLEC1 (DLEC1 cilia and flagella associated protein)

2003-02-01  

Identity

HGNC
LOCATION
3p22.2
LOCUSID
ALIAS
CFAP81,DLC-1,DLC1,F56,FAP81
FUSION GENES

Other Information

Locus ID:

NCBI: 9940
MIM: 604050
HGNC: 2899
Ensembl: ENSG00000008226

Variants:

dbSNP: 9940
ClinVar: 9940
TCGA: ENSG00000008226
COSMIC: DLEC1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000008226ENST00000308059Q9Y238
ENSG00000008226ENST00000346219Q9Y238
ENSG00000008226ENST00000447130Q32W76

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
321445342020Relationship between DLEC1 and PBX3 promoter methylation and the risk and prognosis of gastric cancer in peripheral blood leukocytes.4
331446772020Dlec1 is required for spermatogenesis and male fertility in mice.7
331534312020PM(2.5) exposure and DLEC1 promoter methylation in Taiwan Biobank participants.0
321445342020Relationship between DLEC1 and PBX3 promoter methylation and the risk and prognosis of gastric cancer in peripheral blood leukocytes.4
331446772020Dlec1 is required for spermatogenesis and male fertility in mice.7
331534312020PM(2.5) exposure and DLEC1 promoter methylation in Taiwan Biobank participants.0
306103812019DLEC1 methylation is associated with a better clinical outcome in patients with intrahepatic cholangiocarcinoma of the small duct subtype.7
311765732019Different methylation levels in the KLF4, ATF3 and DLEC1 genes in the myometrium and in corpus uteri mesenchymal tumours as assessed by MS-HRM.6
306103812019DLEC1 methylation is associated with a better clinical outcome in patients with intrahepatic cholangiocarcinoma of the small duct subtype.7
311765732019Different methylation levels in the KLF4, ATF3 and DLEC1 genes in the myometrium and in corpus uteri mesenchymal tumours as assessed by MS-HRM.6
286742222017Small suitability of the DLEC1, MLH1 and TUSC4 mRNA expression analysis as potential prognostic or differentiating markers for NSCLC patients in the Polish population.2
286742222017Small suitability of the DLEC1, MLH1 and TUSC4 mRNA expression analysis as potential prognostic or differentiating markers for NSCLC patients in the Polish population.2
272873422016Expression level and methylation status of three tumor suppressor genes, DLEC1, ITGA9 and MLH1, in non-small cell lung cancer.11
272873422016Expression level and methylation status of three tumor suppressor genes, DLEC1, ITGA9 and MLH1, in non-small cell lung cancer.11
256486352015DLEC1, a 3p tumor suppressor, represses NF-κB signaling and is methylated in prostate cancer.12

Citation

Dessen P

DLEC1 (DLEC1 cilia and flagella associated protein)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/40329/dlec1-(dlec1-cilia-and-flagella-associated-protein)