DLGAP5 (DLG associated protein 5)

2003-02-01  

Identity

HGNC
LOCATION
14q22.3
LOCUSID
ALIAS
DLG7,HURP
FUSION GENES

Other Information

Locus ID:

NCBI: 9787
MIM: 617859
HGNC: 16864
Ensembl: ENSG00000126787

Variants:

dbSNP: 9787
ClinVar: 9787
TCGA: ENSG00000126787
COSMIC: DLGAP5

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000126787ENST00000247191Q15398
ENSG00000126787ENST00000395425Q15398
ENSG00000126787ENST00000554067G3V543
ENSG00000126787ENST00000557645G3V4E5

Expression (GTEx)

0
10
20
30
40
50
60
70

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
191394322009Gene expression profiling reveals a new classification of adrenocortical tumors and identifies molecular predictors of malignancy and survival.82
167698202006HURP controls spindle dynamics to promote proper interkinetochore tension and efficient kinetochore capture.68
125278992003Identification of a novel cell cycle regulated gene, HURP, overexpressed in human hepatocellular carcinoma.47
151459412004Fbx7 functions in the SCF complex regulating Cdk1-cyclin B-phosphorylated hepatoma up-regulated protein (HURP) proteolysis by a proline-rich region.39
183219902008Aurora A regulates the activity of HURP by controlling the accessibility of its microtubule-binding domain.39
159879972005Phosphorylation and stabilization of HURP by Aurora-A: implication of HURP as a transforming target of Aurora-A.38
243246292013Silencing of DLGAP5 by siRNA significantly inhibits the proliferation and invasion of hepatocellular carcinoma cells.28
220489642012Combined expression of BUB1B, DLGAP5, and PINK1 as predictors of poor outcome in adrenocortical tumors: validation in a Brazilian cohort of adult and pediatric patients.27
219246162011HURP regulates chromosome congression by modulating kinesin Kif18A function.20
288083102017Genome-scale analysis identifies NEK2, DLGAP5 and ECT2 as promising diagnostic and prognostic biomarkers in human lung cancer.19

Citation

Dessen P

DLGAP5 (DLG associated protein 5)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/40336/dlgap5-(dlg-associated-protein-5)