Identity
HGNC
LOCATION
22q13.1
LOCUSID
ALIAS
DMC1H,LIM15,dJ199H16.1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 11144
MIM: 602721
HGNC: 2927
Ensembl: ENSG00000100206
Variants:
dbSNP: 11144
ClinVar: 11144
TCGA: ENSG00000100206
COSMIC: DMC1
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Cell Cycle | REACTOME | R-HSA-1640170 |
| Meiosis | REACTOME | R-HSA-1500620 |
| Meiotic recombination | REACTOME | R-HSA-912446 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38142595 | 2024 | Positive and negative regulators of RAD51/DMC1 in homologous recombination and DNA replication. | 2 |
| 38142595 | 2024 | Positive and negative regulators of RAD51/DMC1 in homologous recombination and DNA replication. | 2 |
| 37891173 | 2023 | FIGNL1 AAA+ ATPase remodels RAD51 and DMC1 filaments in pre-meiotic DNA replication and meiotic recombination. | 2 |
| 37891173 | 2023 | FIGNL1 AAA+ ATPase remodels RAD51 and DMC1 filaments in pre-meiotic DNA replication and meiotic recombination. | 2 |
| 35570072 | 2022 | Can PCNA and LIM15 gene expression levels predict sperm retrieval success in men with non-obstructive azoospermia? | 0 |
| 35729697 | 2022 | Recent advances in functional conservation and divergence of recombinase RAD51 and DMC1. | 0 |
| 35946537 | 2022 | MiR-4284 inhibits sensitivity to paclitaxel in human ovarian carcinoma SKOV3ip1 and HeyA8 cells by targeting DMC1. | 1 |
| 35570072 | 2022 | Can PCNA and LIM15 gene expression levels predict sperm retrieval success in men with non-obstructive azoospermia? | 0 |
| 35729697 | 2022 | Recent advances in functional conservation and divergence of recombinase RAD51 and DMC1. | 0 |
| 35946537 | 2022 | MiR-4284 inhibits sensitivity to paclitaxel in human ovarian carcinoma SKOV3ip1 and HeyA8 cells by targeting DMC1. | 1 |
| 33446654 | 2021 | Identification of fidelity-governing factors in human recombinases DMC1 and RAD51 from cryo-EM structures. | 12 |
| 34515795 | 2021 | A pathogenic DMC1 frameshift mutation causes nonobstructive azoospermia but not primary ovarian insufficiency in humans. | 6 |
| 34871438 | 2021 | Mechanisms of distinctive mismatch tolerance between Rad51 and Dmc1 in homologous recombination. | 14 |
| 33446654 | 2021 | Identification of fidelity-governing factors in human recombinases DMC1 and RAD51 from cryo-EM structures. | 12 |
| 34515795 | 2021 | A pathogenic DMC1 frameshift mutation causes nonobstructive azoospermia but not primary ovarian insufficiency in humans. | 6 |
Citation
Dessen P
DMC1 (DNA meiotic recombinase 1)
Atlas Genet Cytogenet Oncol Haematol. 2003-11-01
Online version: http://atlasgeneticsoncology.org/gene/40337/dmc1-(dna-meiotic-recombinase-1)
