DNAJB4 (DnaJ heat shock protein family (Hsp40) member B4)

2003-08-01 Affiliation

Identity

HGNC

DNAJB4

LOCATION

1p31.1

LOCUSID

11080

ALIAS

DNAJW,DjB4,HLJ1

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 11080
MIM: 611327
HGNC: 14886
Ensembl: ENSG00000162616

Variants:

dbSNP: 11080
ClinVar: 11080
TCGA: ENSG00000162616
COSMIC: DNAJB4

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000162616	ENST00000370763	Q9UDY4
ENSG00000162616	ENST00000426517	C9JUL4

Expression (GTEx)

100

150

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Protein levels (Protein atlas)

Not detected

Low

Medium

High

References

Pubmed ID	Year	Title	Citations
36082445	2023	A pleiotropic variant in DNAJB4 is associated with multiple myeloma risk.	1
37510314	2023	Human Endogenous Retrovirus-H-Derived miR-4454 Inhibits the Expression of DNAJB4 and SASH1 in Non-Muscle-Invasive Bladder Cancer.	1
36082445	2023	A pleiotropic variant in DNAJB4 is associated with multiple myeloma risk.	1
37510314	2023	Human Endogenous Retrovirus-H-Derived miR-4454 Inhibits the Expression of DNAJB4 and SASH1 in Non-Muscle-Invasive Bladder Cancer.	1
31221721	2019	Systems-level Analysis Reveals Multiple Modulators of Epithelial-mesenchymal Transition and Identifies DNAJB4 and CD81 as Novel Metastasis Inducers in Breast Cancer.	20
31221721	2019	Systems-level Analysis Reveals Multiple Modulators of Epithelial-mesenchymal Transition and Identifies DNAJB4 and CD81 as Novel Metastasis Inducers in Breast Cancer.	20
29722524	2018	A Targeted Proteomic Approach for Heat Shock Proteins Reveals DNAJB4 as a Suppressor for Melanoma Metastasis.	22
29722524	2018	A Targeted Proteomic Approach for Heat Shock Proteins Reveals DNAJB4 as a Suppressor for Melanoma Metastasis.	22
28481734	2017	HLJ1 (DNAJB4) Gene Is a Novel Biomarker Candidate in Breast Cancer.	14
28481734	2017	HLJ1 (DNAJB4) Gene Is a Novel Biomarker Candidate in Breast Cancer.	14
27065329	2016	HLJ1 is an endogenous Src inhibitor suppressing cancer progression through dual mechanisms.	19
27065329	2016	HLJ1 is an endogenous Src inhibitor suppressing cancer progression through dual mechanisms.	19
24293545	2014	DNAJB4 molecular chaperone distinguishes WT from mutant E-cadherin, determining their fate in vitro and in vivo.	18
24318877	2014	Binding of human nucleotide exchange factors to heat shock protein 70 (Hsp70) generates functionally distinct complexes in vitro.	81
24696714	2014	HLJ1 is a novel biomarker for colorectal carcinoma progression and overall patient survival.	14

Citation

Dessen P

DNAJB4 (DnaJ heat shock protein family (Hsp40) member B4)

Atlas Genet Cytogenet Oncol Haematol. 2003-08-01

Online version: http://atlasgeneticsoncology.org/gene/40343/dnajb4-(dnaj-heat-shock-protein-family-(hsp40)-member-b4)