DPF2 (double PHD fingers 2)

2003-06-01  

Identity

HGNC
DPF2
LOCATION
11q13.1
LOCUSID
5977
ALIAS
CSS7,REQ,UBID4,ubi-d4
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 5977
MIM: 601671
HGNC: 9964
Ensembl: ENSG00000133884

Variants:

dbSNP: 5977
ClinVar: 5977
TCGA: ENSG00000133884
COSMIC: DPF2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000133884ENST00000252268J3KMZ8
ENSG00000133884ENST00000415073Q92785
ENSG00000133884ENST00000528416Q92785
ENSG00000133884ENST00000528416A0A024R582
ENSG00000133884ENST00000531989H0YEI1
ENSG00000133884ENST00000532102E9PN04

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
386973892024DPF2-related Coffin-Siris syndrome type 7 in two generations.0
386973892024DPF2-related Coffin-Siris syndrome type 7 in two generations.0
320244422020BAF45D knockdown decreases cell viability, inhibits colony formation, induces cell apoptosis and S-phase arrest in human pancreatic cancer cells.2
320244422020BAF45D knockdown decreases cell viability, inhibits colony formation, induces cell apoptosis and S-phase arrest in human pancreatic cancer cells.2
294295722018Mutations in the BAF-Complex Subunit DPF2 Are Associated with Coffin-Siris Syndrome.42
294295722018Mutations in the BAF-Complex Subunit DPF2 Are Associated with Coffin-Siris Syndrome.42
284048462017Double Plant Homeodomain Fingers 2 (DPF2) Promotes the Immune Escape of Influenza Virus by Suppressing Beta Interferon Production.7
285334072017Histone-binding of DPF2 mediates its repressive role in myeloid differentiation.18
284048462017Double Plant Homeodomain Fingers 2 (DPF2) Promotes the Immune Escape of Influenza Virus by Suppressing Beta Interferon Production.7
285334072017Histone-binding of DPF2 mediates its repressive role in myeloid differentiation.18
277757142016Selective recognition of histone crotonylation by double PHD fingers of MOZ and DPF2.90
277757142016Selective recognition of histone crotonylation by double PHD fingers of MOZ and DPF2.90
264176822015DPF2 regulates OCT4 protein level and nuclear distribution.12
265715052015SWI/SNF Subunits SMARCA4, SMARCD2 and DPF2 Collaborate in MLL-Rearranged Leukaemia Maintenance.10
264176822015DPF2 regulates OCT4 protein level and nuclear distribution.12

Citation

Dessen P

DPF2 (double PHD fingers 2)

Atlas Genet Cytogenet Oncol Haematol. 2003-06-01

Online version: http://atlasgeneticsoncology.org/gene/40358/dpf2-(double-phd-fingers-2)