Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 117157
MIM: 608510
HGNC: 30416
Ensembl: ENSG00000198574
Variants:
dbSNP: 117157
ClinVar: 117157
TCGA: ENSG00000198574
COSMIC: SH2D1B
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000198574 | ENST00000367929 | O14796 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 27586300 | 2016 | The X-ray Crystallographic Structure of Human EAT2 (SH2D1B). | 1 |
| 27586300 | 2016 | The X-ray Crystallographic Structure of Human EAT2 (SH2D1B). | 1 |
| 24374770 | 2014 | Manipulation of EAT-2 expression promotes induction of multiple beneficial regulatory and effector functions of the human innate immune system as a novel immunomodulatory strategy. | 9 |
| 24687958 | 2014 | EAT-2, a SAP-like adaptor, controls NK cell activation through phospholipase Cγ, Ca++, and Erk, leading to granule polarization. | 48 |
| 24374770 | 2014 | Manipulation of EAT-2 expression promotes induction of multiple beneficial regulatory and effector functions of the human innate immune system as a novel immunomodulatory strategy. | 9 |
| 24687958 | 2014 | EAT-2, a SAP-like adaptor, controls NK cell activation through phospholipase Cγ, Ca++, and Erk, leading to granule polarization. | 48 |
| 16920955 | 2006 | Molecular analysis of NTB-A signaling: a role for EAT-2 in NTB-A-mediated activation of human NK cells. | 18 |
| 16920955 | 2006 | Molecular analysis of NTB-A signaling: a role for EAT-2 in NTB-A-mediated activation of human NK cells. | 18 |
Citation
Dessen P
SH2D1B (SH2 domain containing 1B)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/40390/sh2d1b-(sh2-domain-containing-1b)
