EFS (embryonal Fyn-associated substrate)

2003-05-01  

Identity

HGNC
LOCATION
14q11.2
LOCUSID
ALIAS
CAS3,CASS3,EFS1,EFS2,HEFS,SIN
FUSION GENES

Other Information

Locus ID:

NCBI: 10278
MIM: 609906
HGNC: 16898
Ensembl: ENSG00000100842

Variants:

dbSNP: 10278
ClinVar: 10278
TCGA: ENSG00000100842
COSMIC: EFS

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000100842ENST00000216733O43281
ENSG00000100842ENST00000351354O43281
ENSG00000100842ENST00000429593O43281

Expression (GTEx)

0
50
100
150

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
202374962010New genetic associations detected in a host response study to hepatitis B vaccine.27
218710712011EFS shows biallelic methylation in uveal melanoma with poor prognosis as well as tissue-specific methylation.11
252967362015Decreased expression of EFS is correlated with the advanced prostate cancer.3
261190912015Embryonal Fyn-associated substrate (EFS) and CASS4: The lesser-known CAS protein family members.3
309424872019A new platelet alloantigen (Efsa , HPA-35bw) on glycoprotein IIIa leading to neonatal alloimmune thrombocytopenia.1

Citation

Dessen P

EFS (embryonal Fyn-associated substrate)

Atlas Genet Cytogenet Oncol Haematol. 2003-05-01

Online version: http://atlasgeneticsoncology.org/gene/40417/efs-(embryonal-fyn-associated-substrate)