Identity
HGNC
LOCATION
Xp22.12
LOCUSID
ALIAS
EIF1A,EIF1AP1,EIF4C,eIF-1A,eIF-4C
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 1964
MIM: 300186
HGNC: 3250
Ensembl: ENSG00000173674
Variants:
dbSNP: 1964
ClinVar: 1964
TCGA: ENSG00000173674
COSMIC: EIF1AX
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000173674 | ENST00000379593 | X6RAC9 |
| ENSG00000173674 | ENST00000379607 | P47813 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35080085 | 2022 | Long noncoding RNA EIF1AX-AS1 promotes endometrial cancer cell apoptosis by affecting EIF1AX mRNA stabilization. | 4 |
| 35609001 | 2022 | Clinicopathological features and outcomes of thyroid nodules with EIF1AX mutations. | 3 |
| 35732735 | 2022 | eIF5B and eIF1A reorient initiator tRNA to allow ribosomal subunit joining. | 19 |
| 36371345 | 2022 | EIF1AX mutation in thyroid tumors: a retrospective analysis of cytology, histopathology and co-mutation profiles. | 3 |
| 36589683 | 2022 | XPO1-Mediated EIF1AX Cytoplasmic Relocation Promotes Tumor Migration and Invasion in Endometrial Carcinoma. | 0 |
| 35080085 | 2022 | Long noncoding RNA EIF1AX-AS1 promotes endometrial cancer cell apoptosis by affecting EIF1AX mRNA stabilization. | 4 |
| 35609001 | 2022 | Clinicopathological features and outcomes of thyroid nodules with EIF1AX mutations. | 3 |
| 35732735 | 2022 | eIF5B and eIF1A reorient initiator tRNA to allow ribosomal subunit joining. | 19 |
| 36371345 | 2022 | EIF1AX mutation in thyroid tumors: a retrospective analysis of cytology, histopathology and co-mutation profiles. | 3 |
| 36589683 | 2022 | XPO1-Mediated EIF1AX Cytoplasmic Relocation Promotes Tumor Migration and Invasion in Endometrial Carcinoma. | 0 |
| 34075760 | 2021 | Characterization and Clinical Significance of EIF1AX Mutations and Co-Mutations in Cytologically Indeterminate Thyroid Nodules: A 5-Year Retrospective Analysis. | 5 |
| 34075760 | 2021 | Characterization and Clinical Significance of EIF1AX Mutations and Co-Mutations in Cytologically Indeterminate Thyroid Nodules: A 5-Year Retrospective Analysis. | 5 |
| 31614358 | 2020 | Mutations of GNAQ, GNA11, SF3B1, EIF1AX, PLCB4 and CYSLTR in Uveal Melanoma in Chinese Patients. | 6 |
| 32926483 | 2020 | Transcriptional repression of p21 by EIF1AX promotes the proliferation of breast cancer cells. | 6 |
| 31614358 | 2020 | Mutations of GNAQ, GNA11, SF3B1, EIF1AX, PLCB4 and CYSLTR in Uveal Melanoma in Chinese Patients. | 6 |
Citation
Dessen P
EIF1AX (eukaryotic translation initiation factor 1A X-linked)
Atlas Genet Cytogenet Oncol Haematol. 2003-05-01
Online version: http://atlasgeneticsoncology.org/gene/40423
