Identity
HGNC
LOCATION
2q36.1
LOCUSID
ALIAS
EK8,HEK8,SEK,TYRO1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 2043
MIM: 602188
HGNC: 3388
Ensembl: ENSG00000116106
Variants:
dbSNP: 2043
ClinVar: 2043
TCGA: ENSG00000116106
COSMIC: EPHA4
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36804938 | 2023 | EphA4 signaling is involved in the phenotype of well-differentiated oral squamous cell arcinoma with decreased tumor immunity. | 1 |
| 37477786 | 2023 | Unraveling the Potential of EphA4: A Breakthrough Target and Beacon of Hope for Neurological Diseases. | 2 |
| 36804938 | 2023 | EphA4 signaling is involved in the phenotype of well-differentiated oral squamous cell arcinoma with decreased tumor immunity. | 1 |
| 37477786 | 2023 | Unraveling the Potential of EphA4: A Breakthrough Target and Beacon of Hope for Neurological Diseases. | 2 |
| 34989046 | 2022 | Mechanistic and therapeutic implications of EphA-4 receptor tyrosine kinase in the pathogenesis of Alzheimer's disease. | 4 |
| 35762396 | 2022 | EphA4 regulates white matter remyelination after ischemic stroke through Ephexin-1/RhoA/ROCK signaling pathway. | 6 |
| 34989046 | 2022 | Mechanistic and therapeutic implications of EphA-4 receptor tyrosine kinase in the pathogenesis of Alzheimer's disease. | 4 |
| 35762396 | 2022 | EphA4 regulates white matter remyelination after ischemic stroke through Ephexin-1/RhoA/ROCK signaling pathway. | 6 |
| 33741023 | 2021 | Exosomal miR-106b-5p derived from melanoma cell promotes primary melanocytes epithelial-mesenchymal transition through targeting EphA4. | 14 |
| 33813377 | 2021 | Ephrin Receptor A4 Expression Enhances Migration, Invasion and Neurotropism in Pancreatic Ductal Adenocarcinoma Cells. | 6 |
| 34139238 | 2021 | A cancer mutation promotes EphA4 oligomerization and signaling by altering the conformation of the SAM domain. | 11 |
| 33741023 | 2021 | Exosomal miR-106b-5p derived from melanoma cell promotes primary melanocytes epithelial-mesenchymal transition through targeting EphA4. | 14 |
| 33813377 | 2021 | Ephrin Receptor A4 Expression Enhances Migration, Invasion and Neurotropism in Pancreatic Ductal Adenocarcinoma Cells. | 6 |
| 34139238 | 2021 | A cancer mutation promotes EphA4 oligomerization and signaling by altering the conformation of the SAM domain. | 11 |
| 33090569 | 2020 | EphA4 regulates Aβ production via BACE1 expression in neurons. | 4 |
Citation
Dessen P
EPHA4 (EPH receptor A4)
Atlas Genet Cytogenet Oncol Haematol. 2003-11-01
Online version: http://atlasgeneticsoncology.org/gene/40464/epha4-(eph-receptor-a4)
