Identity
HGNC
LOCATION
4q13.1
LOCUSID
ALIAS
CEK7,EHK-1,EHK1,EK7,HEK7,TYRO4
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 2044
MIM: 600004
HGNC: 3389
Ensembl: ENSG00000145242
Variants:
dbSNP: 2044
ClinVar: 2044
TCGA: ENSG00000145242
COSMIC: EPHA5
RNA/Proteins
Expression (GTEx)
Pathways
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA443560 | Breast Neoplasms | Disease | ClinicalAnnotation | associated | PD | 22843789, 26133776, 26133777, 26763541 | |
| PA445204 | Ovarian Neoplasms | Disease | ClinicalAnnotation | associated | PD | 22843789, 26133776, 26133777, 26763541 | |
| PA450761 | paclitaxel | Chemical | ClinicalAnnotation | associated | PD | 22843789, 26133776, 26133777, 26763541 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35332588 | 2022 | Expression of EPHA5 in lung adenocarcinoma is associated with lymph node metastasis and EGFR mutation. | 2 |
| 36164608 | 2022 | Association between EPHA5 methylation status in peripheral blood leukocytes and the risk and prognosis of gastric cancer. | 1 |
| 36345952 | 2022 | Immunohistochemical evaluation of forkhead box A1 and EphA5 markers in serous ovarian carcinomas, and their impact on the clinical outcome of patients. | 1 |
| 35332588 | 2022 | Expression of EPHA5 in lung adenocarcinoma is associated with lymph node metastasis and EGFR mutation. | 2 |
| 36164608 | 2022 | Association between EPHA5 methylation status in peripheral blood leukocytes and the risk and prognosis of gastric cancer. | 1 |
| 36345952 | 2022 | Immunohistochemical evaluation of forkhead box A1 and EphA5 markers in serous ovarian carcinomas, and their impact on the clinical outcome of patients. | 1 |
| 34109382 | 2021 | Deep learning model reveals potential risk genes for ADHD, especially Ephrin receptor gene EPHA5. | 5 |
| 34109382 | 2021 | Deep learning model reveals potential risk genes for ADHD, especially Ephrin receptor gene EPHA5. | 5 |
| 31823378 | 2020 | Genetic variation in EPHA contributes to sensitivity to paclitaxel-induced peripheral neuropathy. | 9 |
| 32234341 | 2020 | EPHA5 mutation impairs natural killer cell-mediated cytotoxicity against non-small lung cancer cells and promotes cancer cell migration and invasion. | 6 |
| 33288738 | 2020 | EPHA5 mutations predict survival after immunotherapy in lung adenocarcinoma. | 12 |
| 31823378 | 2020 | Genetic variation in EPHA contributes to sensitivity to paclitaxel-induced peripheral neuropathy. | 9 |
| 32234341 | 2020 | EPHA5 mutation impairs natural killer cell-mediated cytotoxicity against non-small lung cancer cells and promotes cancer cell migration and invasion. | 6 |
| 33288738 | 2020 | EPHA5 mutations predict survival after immunotherapy in lung adenocarcinoma. | 12 |
| 27582484 | 2017 | Targeted Sequencing Reveals Low-Frequency Variants in EPHA Genes as Markers of Paclitaxel-Induced Peripheral Neuropathy. | 9 |
Citation
Dessen P
EPHA5 (EPH receptor A5)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/40465/epha5-(eph-receptor-a5)
