BPTF (bromodomain PHD finger transcription factor)

2003-02-01  

Identity

HGNC
BPTF
LOCATION
17q24.2
LOCUSID
2186
ALIAS
FAC1,FALZ,NEDDFL,NURF301
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 2186
MIM: 601819
HGNC: 3581
Ensembl: ENSG00000171634

Variants:

dbSNP: 2186
ClinVar: 2186
TCGA: ENSG00000171634
COSMIC: BPTF

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000171634ENST00000306378Q12830
ENSG00000171634ENST00000321892Q12830
ENSG00000171634ENST00000335221A0A0A0MR81
ENSG00000171634ENST00000342579E9PE19
ENSG00000171634ENST00000424123E7ETD6
ENSG00000171634ENST00000544491F5H176
ENSG00000171634ENST00000544778F5GXF5
ENSG00000171634ENST00000577837J3KSY0
ENSG00000171634ENST00000580465J3KSK9
ENSG00000171634ENST00000581258J3QQQ8
ENSG00000171634ENST00000582467J3QQK4
ENSG00000171634ENST00000583990J3QLW4
ENSG00000171634ENST00000644067A0A2R8Y7Q1

Expression (GTEx)

0
5
10
15
20
25
30
35
40
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
383805092024A role of BPTF in viral oncogenicity delineated through studies of heritable Kaposi sarcoma.0
389404302024NUP98-BPTF promotes oncogenic transformation through PIM1 upregulation.0
383805092024A role of BPTF in viral oncogenicity delineated through studies of heritable Kaposi sarcoma.0
389404302024NUP98-BPTF promotes oncogenic transformation through PIM1 upregulation.0
361536572023The effect of growth hormone treatment in children with novel BPTF gene variants: A report of two cases and literature review.2
369674432023PHF6 recruits BPTF to promote HIF-dependent pathway and progression in YAP-high breast cancer.1
361536572023The effect of growth hormone treatment in children with novel BPTF gene variants: A report of two cases and literature review.2
369674432023PHF6 recruits BPTF to promote HIF-dependent pathway and progression in YAP-high breast cancer.1
365297882022Targeting regulation of VEGF by BPTF in non-small cell lung cancer and its potential clinical significance.2
365297882022Targeting regulation of VEGF by BPTF in non-small cell lung cancer and its potential clinical significance.2
329852202021Upregulation of bromodomain PHD finger transcription factor in ovarian cancer and its critical role for cancer cell proliferation and survival.5
336648552021Downregulated METTL14 accumulates BPTF that reinforces super-enhancers and distal lung metastasis via glycolytic reprogramming in renal cell carcinoma.59
329852202021Upregulation of bromodomain PHD finger transcription factor in ovarian cancer and its critical role for cancer cell proliferation and survival.5
336648552021Downregulated METTL14 accumulates BPTF that reinforces super-enhancers and distal lung metastasis via glycolytic reprogramming in renal cell carcinoma.59
304194222019BPTF promotes hepatocellular carcinoma growth by modulating hTERT signaling and cancer stem cell traits.28

Citation

Dessen P

BPTF (bromodomain PHD finger transcription factor)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/40526/bptf-(bromodomain-phd-finger-transcription-factor)