FGF11 (fibroblast growth factor 11)

2003-02-01  

Identity

HGNC
LOCATION
17p13.1
LOCUSID
ALIAS
FGF-11,FHF-3,FHF3
FUSION GENES

Other Information

Locus ID:

NCBI: 2256
MIM: 601514
HGNC: 3667
Ensembl: ENSG00000161958

Variants:

dbSNP: 2256
ClinVar: 2256
TCGA: ENSG00000161958
COSMIC: FGF11

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000161958ENST00000293829Q92914
ENSG00000161958ENST00000572907I3L4N4
ENSG00000161958ENST00000575082I3L4N4
ENSG00000161958ENST00000575235I3L4N4
ENSG00000161958ENST00000575398I3L4N4

Expression (GTEx)

0
5
10
15
20
25

Pathways

PathwaySourceExternal ID
MAPK signaling pathwayKEGGko04010
Regulation of actin cytoskeletonKEGGko04810
MelanomaKEGGko05218
MAPK signaling pathwayKEGGhsa04010
Regulation of actin cytoskeletonKEGGhsa04810
Pathways in cancerKEGGhsa05200
MelanomaKEGGhsa05218
PI3K-Akt signaling pathwayKEGGhsa04151
PI3K-Akt signaling pathwayKEGGko04151
Ras signaling pathwayKEGGhsa04014
Rap1 signaling pathwayKEGGhsa04015
Rap1 signaling pathwayKEGGko04015
Muscle contractionREACTOMER-HSA-397014
Cardiac conductionREACTOMER-HSA-5576891
Phase 0 - rapid depolarisationREACTOMER-HSA-5576892
Breast cancerKEGGko05224
Breast cancerKEGGhsa05224

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
275384932016Exosomal miR-24-3p impedes T-cell function by targeting FGF11 and serves as a potential prognostic biomarker for nasopharyngeal carcinoma.45
251352782015Infiltrating T cells promote prostate cancer metastasis via modulation of FGF11→miRNA-541→androgen receptor (AR)→MMP9 signaling.21
263238292015Hypoxia-induced fibroblast growth factor 11 stimulates capillary-like endothelial tube formation.7
298521652018T2DM inhibition of endothelial miR-342-3p facilitates angiogenic dysfunction via repression of FGF11 signaling.6
280273902017FGF11 induced by hypoxia interacts with HIF-1α and enhances its stability.2
280973752017Hypoxia-Induced Fibroblast Growth Factor 11 Stimulates Osteoclast-Mediated Resorption of Bone.2
309845502019FGF11 influences 3T3-L1 preadipocyte differentiation by modulating the expression of PPARγ regulators.0

Citation

Dessen P

FGF11 (fibroblast growth factor 11)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/40551/fgf11-(fibroblast-growth-factor-11)