Identity
HGNC
LOCATION
1p35.3
LOCUSID
ALIAS
SRC2,c-fgr,c-src2,p55-Fgr,p55c-fgr,p58-Fgr,p58c-fgr
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 2268
MIM: 164940
HGNC: 3697
Ensembl: ENSG00000000938
Variants:
dbSNP: 2268
ClinVar: 2268
TCGA: ENSG00000000938
COSMIC: FGR
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37116292 | 2023 | Variants in PSMB9 and FGR differentially affect Parkinson's disease risk in GBA and LRRK2 mutation carriers. | 0 |
| 37116292 | 2023 | Variants in PSMB9 and FGR differentially affect Parkinson's disease risk in GBA and LRRK2 mutation carriers. | 0 |
| 34902430 | 2022 | A Model for the Signal Initiation Complex Between Arrestin-3 and the Src Family Kinase Fgr. | 6 |
| 34902430 | 2022 | A Model for the Signal Initiation Complex Between Arrestin-3 and the Src Family Kinase Fgr. | 6 |
| 31790499 | 2019 | Expression of myeloid Src-family kinases is associated with poor prognosis in AML and influences Flt3-ITD kinase inhibitor acquired resistance. | 18 |
| 31790499 | 2019 | Expression of myeloid Src-family kinases is associated with poor prognosis in AML and influences Flt3-ITD kinase inhibitor acquired resistance. | 18 |
| 29763550 | 2018 | Selective Inhibition of the Myeloid Src-Family Kinase Fgr Potently Suppresses AML Cell Growth in Vitro and in Vivo. | 26 |
| 30352950 | 2018 | The Src family kinase Fgr is a transforming oncoprotein that functions independently of SH3-SH2 domain regulation. | 18 |
| 29763550 | 2018 | Selective Inhibition of the Myeloid Src-Family Kinase Fgr Potently Suppresses AML Cell Growth in Vitro and in Vivo. | 26 |
| 30352950 | 2018 | The Src family kinase Fgr is a transforming oncoprotein that functions independently of SH3-SH2 domain regulation. | 18 |
| 28585144 | 2017 | Weighted gene co-expression network analysis of gene modules for the prognosis of esophageal cancer. | 4 |
| 28585144 | 2017 | Weighted gene co-expression network analysis of gene modules for the prognosis of esophageal cancer. | 4 |
| 27324824 | 2016 | A novel approach to detect resistance mechanisms reveals FGR as a factor mediating HDAC inhibitor SAHA resistance in B-cell lymphoma. | 5 |
| 27324824 | 2016 | A novel approach to detect resistance mechanisms reveals FGR as a factor mediating HDAC inhibitor SAHA resistance in B-cell lymphoma. | 5 |
| 25972488 | 2015 | Involvement of the HCK and FGR src-family kinases in FCRL4-mediated immune regulation. | 14 |
Citation
Dessen P
FGR (FGR proto-oncogene, Src family tyrosine kinase)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/40572/fgr-(fgr-proto-oncogene-src-family-tyrosine-kinase)
