Identity
HGNC
LOCATION
1p36.13
LOCUSID
ALIAS
GrinchGEF
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 55160
MIM: 612494
HGNC: 25540
Ensembl: ENSG00000074964
Variants:
dbSNP: 55160
ClinVar: 55160
TCGA: ENSG00000074964
COSMIC: ARHGEF10L
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000074964 | ENST00000167825 | A0A384DVK7 |
| ENSG00000074964 | ENST00000361221 | Q9HCE6 |
| ENSG00000074964 | ENST00000375408 | Q5VXI4 |
| ENSG00000074964 | ENST00000375415 | Q9HCE6 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 32154766 | 2020 | ARHGEF10L expression regulates cell proliferation and migration in gastric tumorigenesis. | 3 |
| 32154766 | 2020 | ARHGEF10L expression regulates cell proliferation and migration in gastric tumorigenesis. | 3 |
| 30444969 | 2019 | ARHGEF10L contributes to liver tumorigenesis through RhoA-ROCK1 signaling and the epithelial-mesenchymal transition. | 8 |
| 30444969 | 2019 | ARHGEF10L contributes to liver tumorigenesis through RhoA-ROCK1 signaling and the epithelial-mesenchymal transition. | 8 |
| 29979793 | 2018 | Variants in genes encoding small GTPases and association with epithelial ovarian cancer susceptibility. | 8 |
| 29979793 | 2018 | Variants in genes encoding small GTPases and association with epithelial ovarian cancer susceptibility. | 8 |
| 19911011 | 2010 | Mutation of ARHGAP9 in patients with coronary spastic angina. | 0 |
| 20379614 | 2010 | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. | 78 |
| 19911011 | 2010 | Mutation of ARHGAP9 in patients with coronary spastic angina. | 0 |
| 20379614 | 2010 | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. | 78 |
| 18849993 | 2008 | Common variants on 1p36 and 1q42 are associated with cutaneous basal cell carcinoma but not with melanoma or pigmentation traits. | 60 |
| 18849993 | 2008 | Common variants on 1p36 and 1q42 are associated with cutaneous basal cell carcinoma but not with melanoma or pigmentation traits. | 60 |
| 16112081 | 2005 | GrinchGEF--a novel Rho-specific guanine nucleotide exchange factor. | 10 |
| 16112081 | 2005 | GrinchGEF--a novel Rho-specific guanine nucleotide exchange factor. | 10 |
Citation
Dessen P
ARHGEF10L (Rho guanine nucleotide exchange factor 10 like)
Atlas Genet Cytogenet Oncol Haematol. 2003-05-01
Online version: http://atlasgeneticsoncology.org/gene/40584/arhgef10l-(rho-guanine-nucleotide-exchange-factor-10-like)
