Identity
HGNC
LOCATION
17q22
LOCUSID
ALIAS
RNF124,SSPCS,URCC
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 54894
MIM: 612482
HGNC: 18505
Ensembl: ENSG00000285897
Variants:
dbSNP: 54894
ClinVar: 54894
TCGA: ENSG00000285897
COSMIC: RNF43
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000285897 | ENST00000648873 | A0A3B3ITA1 |
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38063999 | 2024 | Inherited BRCA1 and RNF43 pathogenic variants in a familial colorectal cancer type X family. | 1 |
| 38225722 | 2024 | RNF43 Inactivation Enhances the B-RAF/MEK Signaling and Creates a Combinatory Therapeutic Target in Cancer Cells. | 1 |
| 38063999 | 2024 | Inherited BRCA1 and RNF43 pathogenic variants in a familial colorectal cancer type X family. | 1 |
| 38225722 | 2024 | RNF43 Inactivation Enhances the B-RAF/MEK Signaling and Creates a Combinatory Therapeutic Target in Cancer Cells. | 1 |
| 36889779 | 2023 | RNF43 Suppressed Triple-Negative Breast Cancer Progression by Inhibiting Wnt/beta-Catenin Pathway. | 0 |
| 37797285 | 2023 | Predictive Impact of RNF43 Mutations in Patients With Proficient Mismatch Repair/Microsatellite Stable BRAFV600E-Mutated Metastatic Colorectal Cancer Treated With Target Therapy or Chemotherapy. | 0 |
| 37848933 | 2023 | Pan-cancer analysis identifies RNF43 as a prognostic, therapeutic and immunological biomarker. | 1 |
| 36889779 | 2023 | RNF43 Suppressed Triple-Negative Breast Cancer Progression by Inhibiting Wnt/beta-Catenin Pathway. | 0 |
| 37797285 | 2023 | Predictive Impact of RNF43 Mutations in Patients With Proficient Mismatch Repair/Microsatellite Stable BRAFV600E-Mutated Metastatic Colorectal Cancer Treated With Target Therapy or Chemotherapy. | 0 |
| 37848933 | 2023 | Pan-cancer analysis identifies RNF43 as a prognostic, therapeutic and immunological biomarker. | 1 |
| 34541672 | 2022 | RNF43 pathogenic Germline variant in a family with colorectal cancer. | 4 |
| 35039505 | 2022 | RNF43/ZNRF3 loss predisposes to hepatocellular-carcinoma by impairing liver regeneration and altering the liver lipid metabolic ground-state. | 12 |
| 35040131 | 2022 | Characterization of RNF43 frameshift mutations that drive Wnt ligand- and R-spondin-dependent colon cancer. | 19 |
| 35066614 | 2022 | RNF43 as a predictor of malignant transformation of pancreatic mucinous cystic neoplasm. | 2 |
| 35254413 | 2022 | Comprehensive Analysis of R-Spondin Fusions and RNF43 Mutations Implicate Novel Therapeutic Options in Colorectal Cancer. | 13 |
Citation
Dessen P
RNF43 (ring finger protein 43)
Atlas Genet Cytogenet Oncol Haematol. 2003-05-01
Online version: http://atlasgeneticsoncology.org/gene/40600/rnf43-(ring-finger-protein-43)
