VGLL3 (vestigial like family member 3)

2003-06-01  

Identity

HGNC
VGLL3
LOCATION
3p12.1
LOCUSID
389136
ALIAS
VGL-3,VGL3
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 389136
MIM: 609980
HGNC: 24327
Ensembl: ENSG00000206538

Variants:

dbSNP: 389136
ClinVar: 389136
TCGA: ENSG00000206538
COSMIC: VGLL3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000206538ENST00000383698A8MV65
ENSG00000206538ENST00000398399A8MV65
ENSG00000206538ENST00000494229H7C571
ENSG00000206538ENST00000637106A0A1B0GTF5

Expression (GTEx)

0
50
100
150
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
123765442002Mammalian vestigial-like 2, a cofactor of TEF-1 and MEF2 transcription factors that promotes skeletal muscle differentiation.48
208427322010YAP1 and VGLL3, encoding two cofactors of TEAD transcription factors, are amplified and overexpressed in a subset of soft tissue sarcomas.39
231525812013Vestigial-like 3 is an inhibitor of adipocyte differentiation.0
234157532013VGLL3 expression is associated with a tumor suppressor phenotype in epithelial ovarian cancer.0
279924042017A gene network regulated by the transcription factor VGLL3 as a promoter of sex-biased autoimmune diseases.0
319928262020VGLL3 is a prognostic biomarker and correlated with clinical pathologic features and immune infiltrates in stomach adenocarcinoma.0

Citation

Dessen P

VGLL3 (vestigial like family member 3)

Atlas Genet Cytogenet Oncol Haematol. 2003-06-01

Online version: http://atlasgeneticsoncology.org/gene/40607/vgll3-(vestigial-like-family-member-3)