FMOD (fibromodulin)

2004-04-01  

Identity

HGNC
LOCATION
1q32.1
LOCUSID
ALIAS
FM,SLRR2E
FUSION GENES

Other Information

Locus ID:

NCBI: 2331
MIM: 600245
HGNC: 3774
Ensembl: ENSG00000122176

Variants:

dbSNP: 2331
ClinVar: 2331
TCGA: ENSG00000122176
COSMIC: FMOD

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000122176ENST00000354955Q06828
ENSG00000122176ENST00000354955A0A024R971
ENSG00000122176ENST00000647586A0A3B3IRN5

Expression (GTEx)

0
100
200
300
400
500
600
700
800

Pathways

PathwaySourceExternal ID
DiseaseREACTOMER-HSA-1643685
Diseases of glycosylationREACTOMER-HSA-3781865
Diseases associated with glycosaminoglycan metabolismREACTOMER-HSA-3560782
Defective B4GALT1 causes B4GALT1-CDG (CDG-2d)REACTOMER-HSA-3656244
Defective CHST6 causes MCDC1REACTOMER-HSA-3656225
MetabolismREACTOMER-HSA-1430728
Metabolism of carbohydratesREACTOMER-HSA-71387
Glycosaminoglycan metabolismREACTOMER-HSA-1630316
Keratan sulfate/keratin metabolismREACTOMER-HSA-1638074
Keratan sulfate biosynthesisREACTOMER-HSA-2022854
Keratan sulfate degradationREACTOMER-HSA-2022857
Extracellular matrix organizationREACTOMER-HSA-1474244
ECM proteoglycansREACTOMER-HSA-3000178
Defective ST3GAL3 causes MCT12 and EIEE15REACTOMER-HSA-3656243

References

Pubmed IDYearTitleCitations
356860322022Fibromodulin Gene Variants (FMOD) as Potential Biomarkers for Prostate Cancer and Benign Prostatic Hyperplasia.3
357371142022Coupled fibromodulin and SOX2 signaling as a critical regulator of metastatic outgrowth in melanoma.6
359823942022A novel ADC targeting cell surface fibromodulin in a mouse model of triple-negative breast cancer.2
356860322022Fibromodulin Gene Variants (FMOD) as Potential Biomarkers for Prostate Cancer and Benign Prostatic Hyperplasia.3
357371142022Coupled fibromodulin and SOX2 signaling as a critical regulator of metastatic outgrowth in melanoma.6
359823942022A novel ADC targeting cell surface fibromodulin in a mouse model of triple-negative breast cancer.2
338877342021Identification of Lumican and Fibromodulin as Hub Genes Associated with Accumulation of Extracellular Matrix in Diabetic Nephropathy.12
342473602021The Association of Cell Surface Fibromodulin Expression and Bladder Carcinoma.2
338877342021Identification of Lumican and Fibromodulin as Hub Genes Associated with Accumulation of Extracellular Matrix in Diabetic Nephropathy.12
342473602021The Association of Cell Surface Fibromodulin Expression and Bladder Carcinoma.2
322201832020[Effect of Silencing FMOD on Proliferation and Migration of H322 Cells and Its Mechanism].1
325305772020FMOD expression in whole blood aids in distinguishing between chronic lymphocytic leukemia and other leukemic lymphoproliferative disorders. A pilot study.0
322201832020[Effect of Silencing FMOD on Proliferation and Migration of H322 Cells and Its Mechanism].1
325305772020FMOD expression in whole blood aids in distinguishing between chronic lymphocytic leukemia and other leukemic lymphoproliferative disorders. A pilot study.0
313052602019CDKN2B upregulation prevents teratoma formation in multipotent fibromodulin-reprogrammed cells.9

Citation

Dessen P

FMOD (fibromodulin)

Atlas Genet Cytogenet Oncol Haematol. 2004-04-01

Online version: http://atlasgeneticsoncology.org/gene/40616/fmod-(fibromodulin)