FCRLA (Fc receptor like A)

2003-06-01  

Identity

HGNC
FCRLA
LOCATION
1q23.3
LOCUSID
84824
ALIAS
FCRL,FCRL1,FCRLM1,FCRLX,FCRLb,FCRLc1,FCRLc2,FCRLd,FCRLe,FCRX,FREB
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 84824
MIM: 606891
HGNC: 18504
Ensembl: ENSG00000132185

Variants:

dbSNP: 84824
ClinVar: 84824
TCGA: ENSG00000132185
COSMIC: FCRLA

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000132185ENST00000236938Q7L513
ENSG00000132185ENST00000294796Q7L513
ENSG00000132185ENST00000309691Q7L513
ENSG00000132185ENST00000349527Q7L513
ENSG00000132185ENST00000350710Q7L513
ENSG00000132185ENST00000367949Q7L513
ENSG00000132185ENST00000367950Q5VXA5
ENSG00000132185ENST00000367953Q7L513
ENSG00000132185ENST00000367957Q7L513
ENSG00000132185ENST00000367959Q7L513
ENSG00000132185ENST00000540521Q7L513
ENSG00000132185ENST00000546024Q7L513

Expression (GTEx)

0
50
100
150
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
329089212020Development and Validation of the B Cell-Associated Fc Receptor-like Molecule-Based Prognostic Signature in Skin Cutaneous Melanoma.3
329089212020Development and Validation of the B Cell-Associated Fc Receptor-like Molecule-Based Prognostic Signature in Skin Cutaneous Melanoma.3
292363552018B cell-specific protein FCRLA is expressed by plasmacytoid dendritic cells in humans.4
292363552018B cell-specific protein FCRLA is expressed by plasmacytoid dendritic cells in humans.4
288795212017FCRLA-A Resident Endoplasmic Reticulum Protein that Associates with Multiple Immunoglobulin Isotypes in B Lineage Cells.4
288795212017FCRLA-A Resident Endoplasmic Reticulum Protein that Associates with Multiple Immunoglobulin Isotypes in B Lineage Cells.4
269805762016Response to Intravenous Cyclophosphamide Treatment for Lupus Nephritis Associated with Polymorphisms in the FCGR2B-FCRLA Locus.6
270152732016FCGR2C Polymorphisms Associated with HIV-1 Vaccine Protection Are Linked to Altered Gene Expression of Fc-γ Receptors in Human B Cells.9
269805762016Response to Intravenous Cyclophosphamide Treatment for Lupus Nephritis Associated with Polymorphisms in the FCGR2B-FCRLA Locus.6
270152732016FCGR2C Polymorphisms Associated with HIV-1 Vaccine Protection Are Linked to Altered Gene Expression of Fc-γ Receptors in Human B Cells.9
237427572013Characterization of human FCRLA isoforms.3
237427572013Characterization of human FCRLA isoforms.3
211494182011FCRLA is a resident endoplasmic reticulum protein that associates with intracellular Igs, IgM, IgG and IgA.18
211494182011FCRLA is a resident endoplasmic reticulum protein that associates with intracellular Igs, IgM, IgG and IgA.18
202374962010New genetic associations detected in a host response study to hepatitis B vaccine.37

Citation

Dessen P

FCRLA (Fc receptor like A)

Atlas Genet Cytogenet Oncol Haematol. 2003-06-01

Online version: http://atlasgeneticsoncology.org/gene/40640/fcrla-(fc-receptor-like-a)