Identity
HGNC
LOCATION
16q24.3
LOCUSID
ALIAS
CILD33,DRC4,GAS11
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 2622
MIM: 605178
HGNC: 4166
Ensembl: ENSG00000141013
Variants:
dbSNP: 2622
ClinVar: 2622
TCGA: ENSG00000141013
COSMIC: GAS8
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Signal Transduction | REACTOME | R-HSA-162582 |
| Signaling by Hedgehog | REACTOME | R-HSA-5358351 |
| Hedgehog 'on' state | REACTOME | R-HSA-5632684 |
| Activation of SMO | REACTOME | R-HSA-5635838 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33942556 | 2021 | LncRNA GAS8-AS1 downregulates lncRNA NEAT1 to inhibit glioblastoma cell proliferation. | 6 |
| 33942556 | 2021 | LncRNA GAS8-AS1 downregulates lncRNA NEAT1 to inhibit glioblastoma cell proliferation. | 6 |
| 32165089 | 2020 | Expression analysis of growth arrest specific 8 and its anti-sense in breast cancer tissues. | 1 |
| 32165089 | 2020 | Expression analysis of growth arrest specific 8 and its anti-sense in breast cancer tissues. | 1 |
| 31003831 | 2019 | GAS8 and its naturally occurring antisense RNA as biomarkers in multiple sclerosis. | 5 |
| 31003831 | 2019 | GAS8 and its naturally occurring antisense RNA as biomarkers in multiple sclerosis. | 5 |
| 29327301 | 2018 | LncRNA GAS8-AS1 inhibits cell proliferation through ATG5-mediated autophagy in papillary thyroid cancer. | 29 |
| 30228180 | 2018 | The long noncoding RNA GAS8-AS1 suppresses hepatocarcinogenesis by epigenetically activating the tumor suppressor GAS8. | 27 |
| 29327301 | 2018 | LncRNA GAS8-AS1 inhibits cell proliferation through ATG5-mediated autophagy in papillary thyroid cancer. | 29 |
| 30228180 | 2018 | The long noncoding RNA GAS8-AS1 suppresses hepatocarcinogenesis by epigenetically activating the tumor suppressor GAS8. | 27 |
| 27120127 | 2016 | Mutations in GAS8, a Gene Encoding a Nexin-Dynein Regulatory Complex Subunit, Cause Primary Ciliary Dyskinesia with Axonemal Disorganization. | 21 |
| 27472056 | 2016 | Mutation of Growth Arrest Specific 8 Reveals a Role in Motile Cilia Function and Human Disease. | 20 |
| 27120127 | 2016 | Mutations in GAS8, a Gene Encoding a Nexin-Dynein Regulatory Complex Subunit, Cause Primary Ciliary Dyskinesia with Axonemal Disorganization. | 21 |
| 27472056 | 2016 | Mutation of Growth Arrest Specific 8 Reveals a Role in Motile Cilia Function and Human Disease. | 20 |
| 26387594 | 2015 | Loss-of-Function GAS8 Mutations Cause Primary Ciliary Dyskinesia and Disrupt the Nexin-Dynein Regulatory Complex. | 59 |
Citation
Dessen P
GAS8 (growth arrest specific 8)
Atlas Genet Cytogenet Oncol Haematol. 2003-06-01
Online version: http://atlasgeneticsoncology.org/gene/40688/gas8-(growth-arrest-specific-8)
