Identity
HGNC
LOCATION
17q21.2
LOCUSID
ALIAS
GCN5,GCN5L2,PCAF-b,hGCN5
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 2648
MIM: 602301
HGNC: 4201
Ensembl: ENSG00000108773
Variants:
dbSNP: 2648
ClinVar: 2648
TCGA: ENSG00000108773
COSMIC: KAT2A
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000108773 | ENST00000225916 | Q92830 |
| ENSG00000108773 | ENST00000465682 | K7ERS6 |
| ENSG00000108773 | ENST00000588759 | K7EPC4 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37294531 | 2024 | KAT2A Promotes the Succinylation of PKM2 to Inhibit its Activity and Accelerate Glycolysis of Gastric Cancer. | 2 |
| 38258976 | 2024 | Lysine acetyltransferase KAT2A modulates ferroptosis during colorectal cancer development. | 0 |
| 38575732 | 2024 | GCN5 mediates DNA-PKcs crotonylation for DNA double-strand break repair and determining cancer radiosensitivity. | 0 |
| 37294531 | 2024 | KAT2A Promotes the Succinylation of PKM2 to Inhibit its Activity and Accelerate Glycolysis of Gastric Cancer. | 2 |
| 38258976 | 2024 | Lysine acetyltransferase KAT2A modulates ferroptosis during colorectal cancer development. | 0 |
| 38575732 | 2024 | GCN5 mediates DNA-PKcs crotonylation for DNA double-strand break repair and determining cancer radiosensitivity. | 0 |
| 36764210 | 2023 | Succinylation of CTBP1 mediated by KAT2A suppresses its inhibitory activity on the transcription of CDH1 to promote the progression of prostate cancer. | 5 |
| 37021521 | 2023 | Regulatory mechanisms of GCN5 in osteogenic differentiation of MSCs in periodontitis. | 2 |
| 37725511 | 2023 | RBL2-E2F-GCN5 guide cell fate decisions during tissue specification by regulating cell-cycle-dependent fluctuations of non-cell-autonomous signaling. | 1 |
| 38007639 | 2023 | Integrative analysis of histone acetyltransferase KAT2A in human cancer. | 0 |
| 36764210 | 2023 | Succinylation of CTBP1 mediated by KAT2A suppresses its inhibitory activity on the transcription of CDH1 to promote the progression of prostate cancer. | 5 |
| 37021521 | 2023 | Regulatory mechanisms of GCN5 in osteogenic differentiation of MSCs in periodontitis. | 2 |
| 37725511 | 2023 | RBL2-E2F-GCN5 guide cell fate decisions during tissue specification by regulating cell-cycle-dependent fluctuations of non-cell-autonomous signaling. | 1 |
| 38007639 | 2023 | Integrative analysis of histone acetyltransferase KAT2A in human cancer. | 0 |
| 34654054 | 2022 | KAT2A complexes ATAC and SAGA play unique roles in cell maintenance and identity in hematopoiesis and leukemia. | 9 |
Citation
Dessen P
KAT2A (lysine acetyltransferase 2A)
Atlas Genet Cytogenet Oncol Haematol. 2003-05-01
Online version: http://atlasgeneticsoncology.org/gene/40696/kat2a-(lysine-acetyltransferase-2a)
