Identity
HGNC
LOCATION
20q11.22
LOCUSID
ALIAS
BDA1C,BMP-14,BMP14,CDMP1,DUPANS,LAP-4,LAP4,OS5,SYM1B,SYNS2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 8200
MIM: 601146
HGNC: 4220
Ensembl: ENSG00000125965
Variants:
dbSNP: 8200
ClinVar: 8200
TCGA: ENSG00000125965
COSMIC: GDF5
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000125965 | ENST00000374369 | P43026 |
| ENSG00000125965 | ENST00000374369 | F1T0J1 |
| ENSG00000125965 | ENST00000374372 | P43026 |
| ENSG00000125965 | ENST00000374372 | F1T0J1 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36823651 | 2023 | LINC00313 promotes the proliferation and inhibits the apoptosis of chondrocytes via regulating miR-525-5p/GDF5 axis. | 2 |
| 37817264 | 2023 | The association of growth differentiation factor 5 rs143383 gene polymorphism with osteoarthritis: a systematic review and meta-analysis. | 0 |
| 37895244 | 2023 | Influence of Different Evolutive Forces on GDF5 Gene Variability. | 1 |
| 36823651 | 2023 | LINC00313 promotes the proliferation and inhibits the apoptosis of chondrocytes via regulating miR-525-5p/GDF5 axis. | 2 |
| 37817264 | 2023 | The association of growth differentiation factor 5 rs143383 gene polymorphism with osteoarthritis: a systematic review and meta-analysis. | 0 |
| 37895244 | 2023 | Influence of Different Evolutive Forces on GDF5 Gene Variability. | 1 |
| 35022077 | 2022 | Effect of lentivirus-mediated growth and differentiation factor-5 transfection on differentiation of rabbit nucleus pulposus mesenchymal stem cells. | 2 |
| 35346361 | 2022 | Long non-coding RNA SNHG5 promotes the osteogenic differentiation of bone marrow mesenchymal stem cells via the miR-212-3p/GDF5/SMAD pathway. | 8 |
| 35563063 | 2022 | Regulatory Mechanisms of Prg4 and Gdf5 Expression in Articular Cartilage and Functions in Osteoarthritis. | 12 |
| 35022077 | 2022 | Effect of lentivirus-mediated growth and differentiation factor-5 transfection on differentiation of rabbit nucleus pulposus mesenchymal stem cells. | 2 |
| 35346361 | 2022 | Long non-coding RNA SNHG5 promotes the osteogenic differentiation of bone marrow mesenchymal stem cells via the miR-212-3p/GDF5/SMAD pathway. | 8 |
| 35563063 | 2022 | Regulatory Mechanisms of Prg4 and Gdf5 Expression in Articular Cartilage and Functions in Osteoarthritis. | 12 |
| 33608035 | 2021 | Correlation between growth differentiation factor 5 (rs143383) gene polymorphism and knee osteoarthritis: an updated systematic review and meta-analysis. | 5 |
| 33861510 | 2021 | Frequency of Growth Differentiation Factor 5 rs143383 and asporin D-repeat polymorphisms in patients with hand and knee osteoarthritis in Kurdistan province, Iran. | 3 |
| 33872773 | 2021 | A GDF5 frameshift mutation segregating with Grebe type chondrodysplasia and brachydactyly type C+ in a 6 generations family: Clinical report and mini review. | 3 |
Citation
Dessen P
GDF5 (growth differentiation factor 5)
Atlas Genet Cytogenet Oncol Haematol. 2004-02-01
Online version: http://atlasgeneticsoncology.org/gene/40702/gdf5
