GDF9 (growth differentiation factor 9)

2003-12-01  

Identity

HGNC
LOCATION
5q31.1
LOCUSID
ALIAS
POF14
FUSION GENES

Other Information

Locus ID:

NCBI: 2661
MIM: 601918
HGNC: 4224
Ensembl: ENSG00000164404

Variants:

dbSNP: 2661
ClinVar: 2661
TCGA: ENSG00000164404
COSMIC: GDF9

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000164404ENST00000296875B4DXG3
ENSG00000164404ENST00000378673O60383
ENSG00000164404ENST00000621295B4DXG3
ENSG00000164404ENST00000624492B4DXG3
ENSG00000164404ENST00000624495B4DXG3

Expression (GTEx)

0
5
10
15
20

Pathways

PathwaySourceExternal ID
Ovarian steroidogenesisKEGGhsa04913
Ovarian steroidogenesisKEGGko04913

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
212260762011Integral role of GDF-9 and BMP-15 in ovarian function.60
166450222006Mutations and sequence variants in GDF9 and BMP15 in patients with premature ovarian failure.56
166450222006Mutations and sequence variants in GDF9 and BMP15 in patients with premature ovarian failure.56
162786192005Mutational screening of the coding region of growth differentiation factor 9 gene in Indian women with ovarian failure.43
162786192005Mutational screening of the coding region of growth differentiation factor 9 gene in Indian women with ovarian failure.43
207340642010A large-scale candidate gene association study of age at menarche and age at natural menopause.38
124467162003Effect of intracellular interactions on the processing and secretion of bone morphogenetic protein-15 (BMP-15) and growth and differentiation factor-9. Implication of the aberrant ovarian phenotype of BMP-15 mutant sheep.37
171567812007Growth differentiating factor-9 mutations may be associated with premature ovarian failure.36
262544682015Cumulin, an Oocyte-secreted Heterodimer of the Transforming Growth Factor-β Family, Is a Potent Activator of Granulosa Cells and Improves Oocyte Quality.33
169541622006Novel variants in growth differentiation factor 9 in mothers of dizygotic twins.32

Citation

Dessen P

GDF9 (growth differentiation factor 9)

Atlas Genet Cytogenet Oncol Haematol. 2003-12-01

Online version: http://atlasgeneticsoncology.org/gene/40704/gdf9-(growth-differentiation-factor-9)