Identity
HGNC
LOCATION
5p13.2
LOCUSID
ALIAS
ATF,ATF1,ATF2,HFB1-GDNF,HSCR3
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 2668
MIM: 600837
HGNC: 4232
Ensembl: ENSG00000168621
Variants:
dbSNP: 2668
ClinVar: 2668
TCGA: ENSG00000168621
COSMIC: GDNF
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA447321 | Depressive Disorder, Major | Disease | ClinicalAnnotation | associated | PD | 24577123 | |
| PA450801 | paroxetine | Chemical | ClinicalAnnotation | associated | PD | 24577123 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37718594 | 2024 | Distinct serum GDNF coupling with brain structural and functional changes underlies cognitive status in Parkinson's disease. | 1 |
| 37858511 | 2024 | Plasma GDNF levels in spinal dysraphism and its relation with neurological impairment in children: A point of care study. | 0 |
| 38307947 | 2024 | The significance of glial cell line-derived neurotrophic factor analysis in Progressive Supranuclear Palsy. | 2 |
| 38674063 | 2024 | MicroRNA-Mediated Suppression of Glial Cell Line-Derived Neurotrophic Factor Expression Is Modulated by a Schizophrenia-Associated Non-Coding Polymorphism. | 0 |
| 37718594 | 2024 | Distinct serum GDNF coupling with brain structural and functional changes underlies cognitive status in Parkinson's disease. | 1 |
| 37858511 | 2024 | Plasma GDNF levels in spinal dysraphism and its relation with neurological impairment in children: A point of care study. | 0 |
| 38307947 | 2024 | The significance of glial cell line-derived neurotrophic factor analysis in Progressive Supranuclear Palsy. | 2 |
| 38674063 | 2024 | MicroRNA-Mediated Suppression of Glial Cell Line-Derived Neurotrophic Factor Expression Is Modulated by a Schizophrenia-Associated Non-Coding Polymorphism. | 0 |
| 36765275 | 2023 | GDNF-RET signaling and EGR1 form a positive feedback loop that promotes tamoxifen resistance via cyclin D1. | 2 |
| 37061618 | 2023 | High expression of the RET receptor tyrosine kinase and its ligand GDNF identifies a high-risk subset of estrogen receptor positive breast cancer. | 1 |
| 37410316 | 2023 | Finding an Optimal Level of GDNF Overexpression: Insights from Dopamine Cycling. | 0 |
| 37786347 | 2023 | Human Neural Progenitors Expressing GDNF Enhance Retinal Protection in a Rodent Model of Retinal Degeneration. | 1 |
| 38069144 | 2023 | Reduced Levels of Lacrimal Glial Cell Line-Derived Neurotrophic Factor (GDNF) in Patients with Focal Epilepsy and Focal Epilepsy with Comorbid Depression: A Biomarker Candidate. | 0 |
| 36765275 | 2023 | GDNF-RET signaling and EGR1 form a positive feedback loop that promotes tamoxifen resistance via cyclin D1. | 2 |
| 37061618 | 2023 | High expression of the RET receptor tyrosine kinase and its ligand GDNF identifies a high-risk subset of estrogen receptor positive breast cancer. | 1 |
Citation
Dessen P
GDNF (glial cell derived neurotrophic factor)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/40705/gdnf-(glial-cell-derived-neurotrophic-factor)
