Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 2782
MIM: 139380
HGNC: 4396
Ensembl: ENSG00000078369
Variants:
dbSNP: 2782
ClinVar: 2782
TCGA: ENSG00000078369
COSMIC: GNB1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA33384 | PLCB1 | Gene | Pathway | associated | |||
| PA33385 | PLCB2 | Gene | Pathway | associated | |||
| PA33386 | PLCB3 | Gene | Pathway | associated | |||
| PA33387 | PLCB4 | Gene | Pathway | associated |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37453880 | 2023 | Atypical clinical course in two patients with GNB1 variants who developed acute encephalopathy. | 1 |
| 37453880 | 2023 | Atypical clinical course in two patients with GNB1 variants who developed acute encephalopathy. | 1 |
| 35192430 | 2022 | Shikonin induces cell autophagy via modulating the microRNA -545-3p/guanine nucleotide binding protein beta polypeptide 1 axis, thereby disrupting cellular carcinogenesis in colon cancer. | 4 |
| 35193469 | 2022 | AFAP1 antisense RNA 1 promotes retinoblastoma progression by sponging microRNA miR-545-3p that targets G protein subunit beta 1. | 3 |
| 35604143 | 2022 | G Protein Subunit β1 Facilitates Influenza A Virus Replication by Promoting the Nuclear Import of PB2. | 4 |
| 35192430 | 2022 | Shikonin induces cell autophagy via modulating the microRNA -545-3p/guanine nucleotide binding protein beta polypeptide 1 axis, thereby disrupting cellular carcinogenesis in colon cancer. | 4 |
| 35193469 | 2022 | AFAP1 antisense RNA 1 promotes retinoblastoma progression by sponging microRNA miR-545-3p that targets G protein subunit beta 1. | 3 |
| 35604143 | 2022 | G Protein Subunit β1 Facilitates Influenza A Virus Replication by Promoting the Nuclear Import of PB2. | 4 |
| 33427398 | 2021 | Genotype-phenotype correlation in GNB1-related neurodevelopmental disorder: Potential association of p.Leu95Pro with cleft palate. | 3 |
| 34022220 | 2021 | Gβγ translocation to the Golgi apparatus activates ARF1 to spatiotemporally regulate G protein-coupled receptor signaling to MAPK. | 8 |
| 33427398 | 2021 | Genotype-phenotype correlation in GNB1-related neurodevelopmental disorder: Potential association of p.Leu95Pro with cleft palate. | 3 |
| 34022220 | 2021 | Gβγ translocation to the Golgi apparatus activates ARF1 to spatiotemporally regulate G protein-coupled receptor signaling to MAPK. | 8 |
| 29174093 | 2018 | Novel GNB1 de novo mutation in a patient with neurodevelopmental disorder and cutaneous mastocytosis: Clinical report and literature review. | 14 |
| 30194818 | 2018 | Refining the phenotype associated with GNB1 mutations: Clinical data on 18 newly identified patients and review of the literature. | 25 |
| 29174093 | 2018 | Novel GNB1 de novo mutation in a patient with neurodevelopmental disorder and cutaneous mastocytosis: Clinical report and literature review. | 14 |
Citation
Dessen P
GNB1 (G protein subunit beta 1)
Atlas Genet Cytogenet Oncol Haematol. 2003-05-01
Online version: http://atlasgeneticsoncology.org/gene/40728/gnb1-(g-protein-subunit-beta-1)
