Identity
HGNC
LOCATION
22q11.21
LOCUSID
ALIAS
DGCRK3,FKSG1,GY2,WDR14,WDVCF
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 54584
MIM: 610778
HGNC: 4397
Ensembl: ENSG00000185838
Variants:
dbSNP: 54584
ClinVar: 54584
TCGA: ENSG00000185838
COSMIC: GNB1L
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000185838 | ENST00000329517 | Q9BYB4 |
| ENSG00000185838 | ENST00000403325 | Q9BYB4 |
| ENSG00000185838 | ENST00000405009 | Q9BYB4 |
| ENSG00000185838 | ENST00000453108 | C9JPQ6 |
Expression (GTEx)
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA33384 | PLCB1 | Gene | Pathway | associated | |||
| PA33385 | PLCB2 | Gene | Pathway | associated | |||
| PA33386 | PLCB3 | Gene | Pathway | associated | |||
| PA33387 | PLCB4 | Gene | Pathway | associated |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33932639 | 2021 | Sequencing of the coding regions of GNBIL on chromosome 22q11.2 as a risk gene of schizophrenia. | 0 |
| 33932639 | 2021 | Sequencing of the coding regions of GNBIL on chromosome 22q11.2 as a risk gene of schizophrenia. | 0 |
| 24831436 | 2015 | The schizophrenia/bipolar disorder candidate gene GNB1L is regulated in human temporal cortex by a cis-acting element located within the 3'-region. | 1 |
| 24831436 | 2015 | The schizophrenia/bipolar disorder candidate gene GNB1L is regulated in human temporal cortex by a cis-acting element located within the 3'-region. | 1 |
| 20538345 | 2011 | Association study between GNB1L and three major mental disorders in Chinese Han populations. | 6 |
| 20538345 | 2011 | Association study between GNB1L and three major mental disorders in Chinese Han populations. | 6 |
| 20538345 | 2011 | Association study between GNB1L and three major mental disorders in Chinese Han populations. | 6 |
| 20538345 | 2011 | Association study between GNB1L and three major mental disorders in Chinese Han populations. | 6 |
| 19011233 | 2010 | Supportive evidence for reduced expression of GNB1L in schizophrenia. | 13 |
| 19011233 | 2010 | Supportive evidence for reduced expression of GNB1L in schizophrenia. | 13 |
| 20860462 | 2010 | β-blocker therapy and heart rate control during exercise testing in the general population: role of a common G-protein β-3 subunit variant. | 3 |
| 19011233 | 2010 | Supportive evidence for reduced expression of GNB1L in schizophrenia. | 13 |
| 19011233 | 2010 | Supportive evidence for reduced expression of GNB1L in schizophrenia. | 13 |
| 20860462 | 2010 | β-blocker therapy and heart rate control during exercise testing in the general population: role of a common G-protein β-3 subunit variant. | 3 |
| 18003636 | 2008 | Strong evidence that GNB1L is associated with schizophrenia. | 28 |
Citation
Dessen P
GNB1L (G protein subunit beta 1 like)
Atlas Genet Cytogenet Oncol Haematol. 2003-05-01
Online version: http://atlasgeneticsoncology.org/gene/40729/gnb1l-(g-protein-subunit-beta-1-like)
