Identity
HGNC
LOCATION
1p36.22
LOCUSID
ALIAS
CORTRD1,G6PDH,GDH,H6PDH
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9563
MIM: 138090
HGNC: 4795
Ensembl: ENSG00000049239
Variants:
dbSNP: 9563
ClinVar: 9563
TCGA: ENSG00000049239
COSMIC: H6PD
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000049239 | ENST00000377403 | O95479 |
| ENSG00000049239 | ENST00000602477 | R4GMU1 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33250514 | 2021 | Tumor-suppressive microRNA-551b-3p targets H6PD to inhibit gallbladder cancer progression. | 3 |
| 33250514 | 2021 | Tumor-suppressive microRNA-551b-3p targets H6PD to inhibit gallbladder cancer progression. | 3 |
| 29295867 | 2018 | Hexose-6-phosphate dehydrogenase controls cancer cell proliferation and migration through pleiotropic effects on the unfolded-protein response, calcium homeostasis, and redox balance. | 15 |
| 29295867 | 2018 | Hexose-6-phosphate dehydrogenase controls cancer cell proliferation and migration through pleiotropic effects on the unfolded-protein response, calcium homeostasis, and redox balance. | 15 |
| 28370139 | 2017 | Mutations in the tetramer interface of human glucose-6-phosphate dehydrogenase reveals kinetic differences between oligomeric states. | 6 |
| 28370139 | 2017 | Mutations in the tetramer interface of human glucose-6-phosphate dehydrogenase reveals kinetic differences between oligomeric states. | 6 |
| 26860459 | 2016 | Cortisol promotes endoplasmic glucose production via pyridine nucleotide redox. | 2 |
| 26860459 | 2016 | Cortisol promotes endoplasmic glucose production via pyridine nucleotide redox. | 2 |
| 26337086 | 2015 | Inhibition of glucose-6-phosphate dehydrogenase sensitizes cisplatin-resistant cells to death. | 60 |
| 26452272 | 2015 | Association Analysis between the Polymorphisms of HSD11B1 and H6PD and Risk of Polycystic Ovary Syndrome in Chinese Population. | 2 |
| 26337086 | 2015 | Inhibition of glucose-6-phosphate dehydrogenase sensitizes cisplatin-resistant cells to death. | 60 |
| 26452272 | 2015 | Association Analysis between the Polymorphisms of HSD11B1 and H6PD and Risk of Polycystic Ovary Syndrome in Chinese Population. | 2 |
| 24631573 | 2014 | Reduced cellular Mg²⁺ content enhances hexose 6-phosphate dehydrogenase activity and expression in HepG2 and HL-60 cells. | 1 |
| 24631573 | 2014 | Reduced cellular Mg²⁺ content enhances hexose 6-phosphate dehydrogenase activity and expression in HepG2 and HL-60 cells. | 1 |
| 23979790 | 2013 | The expression of 11β-HSDs, GR, and H6PDH in subcutaneous adipose tissue from polycystic ovary syndrome subjects. | 5 |
Citation
Dessen P
H6PD (hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase)
Atlas Genet Cytogenet Oncol Haematol. 2003-05-01
Online version: http://atlasgeneticsoncology.org/gene/40786/h6pd-(hexose-6-phosphate-dehydrogenase-glucose-1-dehydrogenase)
