HOPX (HOP homeobox)

2003-06-01  

Identity

HGNC
HOPX
LOCATION
4q12
LOCUSID
84525
ALIAS
CAMEO,HOD,HOP,LAGY,NECC1,OB1,SMAP31,TOTO
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 84525
MIM: 607275
HGNC: 24961
Ensembl: ENSG00000171476

Variants:

dbSNP: 84525
ClinVar: 84525
TCGA: ENSG00000171476
COSMIC: HOPX

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000171476ENST00000317745Q9BPY8
ENSG00000171476ENST00000337881Q9BPY8
ENSG00000171476ENST00000381255Q9BPY8
ENSG00000171476ENST00000381260Q9BPY8
ENSG00000171476ENST00000420433Q9BPY8
ENSG00000171476ENST00000503639Q9BPY8
ENSG00000171476ENST00000508121Q9BPY8
ENSG00000171476ENST00000553379Q9BPY8
ENSG00000171476ENST00000554144Q9BPY8
ENSG00000171476ENST00000555760Q9BPY8
ENSG00000171476ENST00000556376Q9BPY8
ENSG00000171476ENST00000556614Q9BPY8

Expression (GTEx)

0
100
200
300
400
500
600
700
800
900
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
384105162024Homeodomain-only protein suppresses proliferation and contributes to differentiation- and age-related reduced CD8(+) T cell expansion.0
384105162024Homeodomain-only protein suppresses proliferation and contributes to differentiation- and age-related reduced CD8(+) T cell expansion.0
338450782021HOPX Exhibits Oncogenic Activity during Squamous Skin Carcinogenesis.3
349439642021HOPX Plays a Critical Role in Antiretroviral Drugs Induced Epigenetic Modification and Cardiac Hypertrophy.3
338450782021HOPX Exhibits Oncogenic Activity during Squamous Skin Carcinogenesis.3
349439642021HOPX Plays a Critical Role in Antiretroviral Drugs Induced Epigenetic Modification and Cardiac Hypertrophy.3
326473042020HOPX regulates bone marrow-derived mesenchymal stromal cell fate determination via suppression of adipogenic gene pathways.8
330403962020Molecular basis of the interaction of Hsp90 with its co-chaperone Hop.11
326473042020HOPX regulates bone marrow-derived mesenchymal stromal cell fate determination via suppression of adipogenic gene pathways.8
330403962020Molecular basis of the interaction of Hsp90 with its co-chaperone Hop.11
309590412019HOPX Is a ZNF750 Target that Promotes Late Epidermal Differentiation.3
310924202019Differential Prognostic Relevance of Promoter DNA Methylation of CDO1 and HOPX in Primary Breast Cancer.4
311155072019ΜicroRNA‑421 promotes the progression of non‑small cell lung cancer by targeting HOPX and regulating the Wnt/β‑catenin signaling pathway.11
309590412019HOPX Is a ZNF750 Target that Promotes Late Epidermal Differentiation.3
310924202019Differential Prognostic Relevance of Promoter DNA Methylation of CDO1 and HOPX in Primary Breast Cancer.4

Citation

Dessen P

HOPX (HOP homeobox)

Atlas Genet Cytogenet Oncol Haematol. 2003-06-01

Online version: http://atlasgeneticsoncology.org/gene/40845/hopx-(hop-homeobox)