HOXC11 (homeobox C11)

2003-02-01  

Identity

HGNC
HOXC11
LOCATION
12q13.13
LOCUSID
3227
ALIAS
HOX3H
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 3227
MIM: 605559
HGNC: 5123
Ensembl: ENSG00000123388

Variants:

dbSNP: 3227
ClinVar: 3227
TCGA: ENSG00000123388
COSMIC: HOXC11

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000123388ENST00000243082J3KMZ0
ENSG00000123388ENST00000546378O43248

Expression (GTEx)

0
1
2
3
4
5
6
7
8
9
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
N/A

References

Pubmed IDYearTitleCitations
368231492023HOXC11 drives lung adenocarcinoma progression through transcriptional regulation of SPHK1.1
368231492023HOXC11 drives lung adenocarcinoma progression through transcriptional regulation of SPHK1.1
344157922021HOXC11 Expression Is Associated with the Progression of Colon Adenocarcinoma and Is a Prognostic Biomarker.2
344157922021HOXC11 Expression Is Associated with the Progression of Colon Adenocarcinoma and Is a Prognostic Biomarker.2
319234222020HOXC11 functions as a novel oncogene in human colon adenocarcinoma and kidney renal clear cell carcinoma.9
319234222020HOXC11 functions as a novel oncogene in human colon adenocarcinoma and kidney renal clear cell carcinoma.9
311814452019MicroRNA-1197 downregulation inhibits proliferation and migration in human non- small cell lung cancer cells by upregulating HOXC11.11
311814452019MicroRNA-1197 downregulation inhibits proliferation and migration in human non- small cell lung cancer cells by upregulating HOXC11.11
254768562015Overexpression of HOXC11 homeobox gene in clear cell renal cell carcinoma induces cellular proliferation and is associated with poor prognosis.16
254768562015Overexpression of HOXC11 homeobox gene in clear cell renal cell carcinoma induces cellular proliferation and is associated with poor prognosis.16
201451292010Interaction of developmental transcription factor HOXC11 with steroid receptor coactivator SRC-1 mediates resistance to endocrine therapy in breast cancer [corrected].39
201451292010Interaction of developmental transcription factor HOXC11 with steroid receptor coactivator SRC-1 mediates resistance to endocrine therapy in breast cancer [corrected].39
174884782007HOXC6 and HOXC11 increase transcription of S100beta gene in BrdU-induced in vitro differentiation of GOTO neuroblastoma cells into Schwannian cells.17
174884782007HOXC6 and HOXC11 increase transcription of S100beta gene in BrdU-induced in vitro differentiation of GOTO neuroblastoma cells into Schwannian cells.17

Citation

Dessen P

HOXC11 (homeobox C11)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/40852/hoxc11-(homeobox-c11)