Identity
HGNC
LOCATION
6p21.33
LOCUSID
ALIAS
HEL-S-103,HSP70-1,HSP70-1A,HSP70-2,HSP70.1,HSP70.2,HSP70I,HSP72,HSPA1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3303
MIM: 140550
HGNC: 5232
Ensembl: ENSG00000204389
Variants:
dbSNP: 3303
ClinVar: 3303
TCGA: ENSG00000204389
COSMIC: HSPA1A
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000204389 | ENST00000375651 | P0DMV8 |
| ENSG00000204389 | ENST00000375651 | A8K5I0 |
| ENSG00000204389 | ENST00000608703 | V9GZ37 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA448785 | carbamazepine | Chemical | ClinicalAnnotation | associated | PD | 16538175 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38703814 | 2024 | Heat shock protein 72 supports extracellular matrix production in metastatic mammary tumors. | 0 |
| 38703814 | 2024 | Heat shock protein 72 supports extracellular matrix production in metastatic mammary tumors. | 0 |
| 36345598 | 2023 | Analysis of the heat shock protein 70 (HSP70) genetic variants in nonsegmental vitiligo patients. | 1 |
| 36519896 | 2023 | Heat Shock Protein Family A Member 1 Promotes Intracellular Amplification of Hepatitis B Virus Covalently Closed Circular DNA. | 1 |
| 36814356 | 2023 | Downregulation of Heat Shock Protein 72 Contributes to Fibrostenosis in Crohn's Disease. | 1 |
| 37254218 | 2023 | ZNF330/NOA36 interacts with HSPA1 and HSPA8 and modulates cell cycle and proliferation in response to heat shock in HEK293 cells. | 2 |
| 37298493 | 2023 | Heat Shock Protein 70 Is Involved in the Efficiency of Preconditioning with Cyclosporine A in Renal Ischemia Reperfusion Injury by Modulating Mitochondrial Functions. | 0 |
| 37525035 | 2023 | A Genomic Study of the Japanese Population Focusing on the Glucocorticoid Receptor Interactome Highlights Distinct Genetic Characteristics Associated with Stress Response. | 0 |
| 37926404 | 2023 | Association of elevated extracellular HSP72 in albuminuria with systemic inflammation and disease progression in type 2 diabetic kidney disease. | 0 |
| 36345598 | 2023 | Analysis of the heat shock protein 70 (HSP70) genetic variants in nonsegmental vitiligo patients. | 1 |
| 36519896 | 2023 | Heat Shock Protein Family A Member 1 Promotes Intracellular Amplification of Hepatitis B Virus Covalently Closed Circular DNA. | 1 |
| 36814356 | 2023 | Downregulation of Heat Shock Protein 72 Contributes to Fibrostenosis in Crohn's Disease. | 1 |
| 37254218 | 2023 | ZNF330/NOA36 interacts with HSPA1 and HSPA8 and modulates cell cycle and proliferation in response to heat shock in HEK293 cells. | 2 |
| 37298493 | 2023 | Heat Shock Protein 70 Is Involved in the Efficiency of Preconditioning with Cyclosporine A in Renal Ischemia Reperfusion Injury by Modulating Mitochondrial Functions. | 0 |
| 37525035 | 2023 | A Genomic Study of the Japanese Population Focusing on the Glucocorticoid Receptor Interactome Highlights Distinct Genetic Characteristics Associated with Stress Response. | 0 |
Citation
Dessen P
HSPA1A (heat shock protein family A (Hsp70) member 1A)
Atlas Genet Cytogenet Oncol Haematol. 2003-08-01
Online version: http://atlasgeneticsoncology.org/gene/40871/hspa1a-(heat-shock-protein-family-a-(hsp70)-member-1a)
