HSPA1B (heat shock protein family A (Hsp70) member 1B)

2003-06-01  

Identity

HGNC
LOCATION
6p21.33
LOCUSID
ALIAS
HSP70-1,HSP70-1B,HSP70-2,HSP70.1,HSP70.2,HSP72,HSPA1,HSX70
FUSION GENES

Other Information

Locus ID:

NCBI: 3304
MIM: 603012
HGNC: 5233
Ensembl: ENSG00000204388

Variants:

dbSNP: 3304
ClinVar: 3304
TCGA: ENSG00000204388
COSMIC: HSPA1B

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000204388ENST00000375650P0DMV9
ENSG00000204388ENST00000375650A8K5I0

Expression (GTEx)

0
50
100
150

Pathways

PathwaySourceExternal ID
MAPK signaling pathwayKEGGko04010
Antigen processing and presentationKEGGko04612
MAPK signaling pathwayKEGGhsa04010
Antigen processing and presentationKEGGhsa04612
EndocytosisKEGGko04144
EndocytosisKEGGhsa04144
SpliceosomeKEGGko03040
SpliceosomeKEGGhsa03040
Protein processing in endoplasmic reticulumKEGGko04141
Protein processing in endoplasmic reticulumKEGGhsa04141
ToxoplasmosisKEGGko05145
ToxoplasmosisKEGGhsa05145
MeaslesKEGGko05162
MeaslesKEGGhsa05162
Influenza AKEGGko05164
Influenza AKEGGhsa05164
Spliceosome, Prp19/CDC5L complexKEGGhsa_M00353
Spliceosome, 35S U5-snRNPKEGGhsa_M00355
LegionellosisKEGGko05134
LegionellosisKEGGhsa05134
Epstein-Barr virus infectionKEGGhsa05169
Epstein-Barr virus infectionKEGGko05169
Estrogen signaling pathwayKEGGhsa04915
Estrogen signaling pathwayKEGGko04915
Spliceosome, Prp19/CDC5L complexKEGGM00353
Spliceosome, 35S U5-snRNPKEGGM00355
Immune SystemREACTOMER-HSA-168256
Innate Immune SystemREACTOMER-HSA-168249
Cellular responses to stressREACTOMER-HSA-2262752
Cellular response to heat stressREACTOMER-HSA-3371556
HSF1-dependent transactivationREACTOMER-HSA-3371571
Attenuation phaseREACTOMER-HSA-3371568
Regulation of HSF1-mediated heat shock responseREACTOMER-HSA-3371453
Longevity regulating pathway - multiple speciesKEGGko04213
Longevity regulating pathway - multiple speciesKEGGhsa04213
Neutrophil degranulationREACTOMER-HSA-6798695

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
363455982023Analysis of the heat shock protein 70 (HSP70) genetic variants in nonsegmental vitiligo patients.1
372831232023Interaction of HSP70-2 gene polymorphism with body mass index and alcohol consumption on the prognosis of Uyghur patients with ischemic heart failure.0
363455982023Analysis of the heat shock protein 70 (HSP70) genetic variants in nonsegmental vitiligo patients.1
372831232023Interaction of HSP70-2 gene polymorphism with body mass index and alcohol consumption on the prognosis of Uyghur patients with ischemic heart failure.0
362916742022Next Generation Sequencing of Genotype Variants and Genetic Association between Heat Shock Proteins HSPA1B Single Nucleotide Polymorphism at the g.31829044 Locus and Heat Tolerance: A Pilot Quasi-Experimental Study.2
365536582022Diagnostic and Prognostic Risk Assessment of Heat Shock Protein HSPA1B rs2763979 Gene Variant in Asthma.2
362916742022Next Generation Sequencing of Genotype Variants and Genetic Association between Heat Shock Proteins HSPA1B Single Nucleotide Polymorphism at the g.31829044 Locus and Heat Tolerance: A Pilot Quasi-Experimental Study.2
365536582022Diagnostic and Prognostic Risk Assessment of Heat Shock Protein HSPA1B rs2763979 Gene Variant in Asthma.2
333099922021Genetic association study of a novel indel polymorphism in HSPA1B with the risk of sudden cardiac death in the Chinese populations.3
342924432021Analysis of HSPA1B (+1267A>G) Genetic Polymorphism in Patients with Vibration Disease in Combination with Metabolic Syndrome.0
333099922021Genetic association study of a novel indel polymorphism in HSPA1B with the risk of sudden cardiac death in the Chinese populations.3
342924432021Analysis of HSPA1B (+1267A>G) Genetic Polymorphism in Patients with Vibration Disease in Combination with Metabolic Syndrome.0
311317552020Association of CYP2C19 and HSP70 Genes Polymorphism with Aspirin- Exacerbated Respiratory Disease in a Kurd Population.3
316420262020Association of HSPA1B Polymorphisms with Paranoid Schizophrenia in a Polish Population.6
320154592020Association of HSPA1B genotypes with psychopathology and neurocognition in patients with the first episode of psychosis: a longitudinal 18-month follow-up study.2

Citation

Dessen P

HSPA1B (heat shock protein family A (Hsp70) member 1B)

Atlas Genet Cytogenet Oncol Haematol. 2003-06-01

Online version: http://atlasgeneticsoncology.org/gene/40872/js/lib/welcome