Identity
HGNC
LOCATION
11q23.1
LOCUSID
ALIAS
HSP27,Hs.78846,LOH11CR1K,MKBP
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3316
MIM: 602179
HGNC: 5247
Ensembl: ENSG00000170276
Variants:
dbSNP: 3316
ClinVar: 3316
TCGA: ENSG00000170276
COSMIC: HSPB2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000170276 | ENST00000304298 | Q16082 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Epstein-Barr virus infection | KEGG | hsa05169 |
| Epstein-Barr virus infection | KEGG | ko05169 |
| Proteoglycans in cancer | KEGG | hsa05205 |
| Proteoglycans in cancer | KEGG | ko05205 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36768927 | 2023 | Evaluation of the Small Heat Shock Protein Family Members HSPB2 and HSPB3 in Bladder Cancer Prognosis and Progression. | 0 |
| 36931492 | 2023 | HSP-27 and HSP-70 negatively regulate protective defence responses from macrophages during mycobacterial infection. | 0 |
| 37606039 | 2023 | HSPB2 facilitates neural regeneration through autophagy for sensorimotor recovery after traumatic brain injury. | 3 |
| 37797796 | 2023 | Phosphorylated Hsp27 promotes adriamycin resistance in breast cancer cells through regulating dual phosphorylation of c-Myc. | 2 |
| 36768927 | 2023 | Evaluation of the Small Heat Shock Protein Family Members HSPB2 and HSPB3 in Bladder Cancer Prognosis and Progression. | 0 |
| 36931492 | 2023 | HSP-27 and HSP-70 negatively regulate protective defence responses from macrophages during mycobacterial infection. | 0 |
| 37606039 | 2023 | HSPB2 facilitates neural regeneration through autophagy for sensorimotor recovery after traumatic brain injury. | 3 |
| 37797796 | 2023 | Phosphorylated Hsp27 promotes adriamycin resistance in breast cancer cells through regulating dual phosphorylation of c-Myc. | 2 |
| 31692031 | 2020 | Molecular chaperone HspB2 inhibited pancreatic cancer cell proliferation via activating p53 downstream gene RPRM, BAI1, and TSAP6. | 14 |
| 32315283 | 2020 | HMGN5 promotes IL-6-induced epithelial-mesenchymal transition of bladder cancer by interacting with Hsp27. | 7 |
| 31692031 | 2020 | Molecular chaperone HspB2 inhibited pancreatic cancer cell proliferation via activating p53 downstream gene RPRM, BAI1, and TSAP6. | 14 |
| 32315283 | 2020 | HMGN5 promotes IL-6-induced epithelial-mesenchymal transition of bladder cancer by interacting with Hsp27. | 7 |
| 31088577 | 2019 | Novel predictive epigenetic signature for temozolomide in non-G-CIMP glioblastomas. | 9 |
| 31088577 | 2019 | Novel predictive epigenetic signature for temozolomide in non-G-CIMP glioblastomas. | 9 |
| 28181153 | 2017 | An interaction study in mammalian cells demonstrates weak binding of HSPB2 to BAG3, which is regulated by HSPB3 and abrogated by HSPB8. | 12 |
Citation
Dessen P
HSPB2 (heat shock protein family B (small) member 2)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/40881/hspb2-(heat-shock-protein-family-b-(small)-member-2)
