ARMC8 (armadillo repeat containing 8)

2003-12-01  

Identity

HGNC
ARMC8
LOCATION
3q22.3
LOCUSID
25852
ALIAS
GID5,HSPC056,S863-2,VID28
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 25852
MIM: 618521
HGNC: 24999
Ensembl: ENSG00000114098

Variants:

dbSNP: 25852
ClinVar: 25852
TCGA: ENSG00000114098
COSMIC: ARMC8

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000114098ENST00000358441Q8IUR7
ENSG00000114098ENST00000461600C9JAA7
ENSG00000114098ENST00000461822Q8IUR7
ENSG00000114098ENST00000463485C9J2I1
ENSG00000114098ENST00000464181H7C4J4
ENSG00000114098ENST00000466749C9J8P8
ENSG00000114098ENST00000468560C9J625
ENSG00000114098ENST00000469044Q8IUR7
ENSG00000114098ENST00000469860H7C5B7
ENSG00000114098ENST00000470549H7C5H2
ENSG00000114098ENST00000470821G5E9V6
ENSG00000114098ENST00000471453Q8IUR7
ENSG00000114098ENST00000471709C9JBY2
ENSG00000114098ENST00000481646Q8IUR7
ENSG00000114098ENST00000485396B7Z637
ENSG00000114098ENST00000489213G5E9V7
ENSG00000114098ENST00000491704Q8IUR7
ENSG00000114098ENST00000538260Q8IUR7

Expression (GTEx)

0
10
20
30
40
50
60
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Immune SystemREACTOMER-HSA-168256
Innate Immune SystemREACTOMER-HSA-168249
Neutrophil degranulationREACTOMER-HSA-6798695

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
374008472023MiR-455-3p inhibits gastric cancer progression by repressing Wnt/β-catenin signaling through binding to ARMC8.3
374008472023MiR-455-3p inhibits gastric cancer progression by repressing Wnt/β-catenin signaling through binding to ARMC8.3
340164862021Downregulation of ARMC8 promotes tumorigenesis through activating Wnt/β-catenin pathway and EMT in cutaneous squamous cell carcinomas.6
340164862021Downregulation of ARMC8 promotes tumorigenesis through activating Wnt/β-catenin pathway and EMT in cutaneous squamous cell carcinomas.6
304828822019Armc8 is an evolutionarily conserved armadillo protein involved in cell-cell adhesion complexes through multiple molecular interactions.6
304828822019Armc8 is an evolutionarily conserved armadillo protein involved in cell-cell adhesion complexes through multiple molecular interactions.6
269440572016Armc8 regulates the invasive ability of hepatocellular carcinoma through E-cadherin/catenin complex.13
277125952016Armadillo Repeat-Containing Protein 8 (ARMC8) Silencing Inhibits Proliferation and Invasion in Osteosarcoma Cells.8
269440572016Armc8 regulates the invasive ability of hepatocellular carcinoma through E-cadherin/catenin complex.13
277125952016Armadillo Repeat-Containing Protein 8 (ARMC8) Silencing Inhibits Proliferation and Invasion in Osteosarcoma Cells.8
260816212015ARMc8 indicates aggressive colon cancers and promotes invasiveness and migration of colon cancer cells.11
262328632015A novel biomarker ARMc8 promotes the malignant progression of ovarian cancer.12
260816212015ARMc8 indicates aggressive colon cancers and promotes invasiveness and migration of colon cancer cells.11
262328632015A novel biomarker ARMc8 promotes the malignant progression of ovarian cancer.12
248946752014ARMC8α promotes proliferation and invasion of non-small cell lung cancer cells by activating the canonical Wnt signaling pathway.17

Citation

Dessen P

ARMC8 (armadillo repeat containing 8)

Atlas Genet Cytogenet Oncol Haematol. 2003-12-01

Online version: http://atlasgeneticsoncology.org/gene/40884/armc8-(armadillo-repeat-containing-8)