HSPE1 (heat shock protein family E (Hsp10) member 1)

2003-08-01  

Identity

HGNC
HSPE1
LOCATION
2q33.1
LOCUSID
3336
ALIAS
CPN10,EPF,GROES,HSP10
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 3336
MIM: 600141
HGNC: 5269
Ensembl: ENSG00000115541

Variants:

dbSNP: 3336
ClinVar: 3336
TCGA: ENSG00000115541
COSMIC: HSPE1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000115541ENST00000233893P61604
ENSG00000115541ENST00000233893A0A384N6A4
ENSG00000115541ENST00000409468B8ZZL8
ENSG00000115541ENST00000409729B8ZZ54

Expression (GTEx)

0
50
100
150
200
250
300
350
400
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
329866592021Overexpression of HSP10 correlates with HSP60 and Mcl-1 levels and predicts poor prognosis in non-small cell lung cancer patients.7
342853022021Structural basis for the structural dynamics of human mitochondrial chaperonin mHsp60.7
329866592021Overexpression of HSP10 correlates with HSP60 and Mcl-1 levels and predicts poor prognosis in non-small cell lung cancer patients.7
342853022021Structural basis for the structural dynamics of human mitochondrial chaperonin mHsp60.7
320606902020An inventory of interactors of the human HSP60/HSP10 chaperonin in the mitochondrial matrix space.14
323176352020Structural basis for active single and double ring complexes in human mitochondrial Hsp60-Hsp10 chaperonin.25
320606902020An inventory of interactors of the human HSP60/HSP10 chaperonin in the mitochondrial matrix space.14
323176352020Structural basis for active single and double ring complexes in human mitochondrial Hsp60-Hsp10 chaperonin.25
279935802017High expression of heat shock protein 10 correlates negatively with estrogen/progesterone receptor status and predicts poor prognosis in invasive ductal breast carcinoma.5
286621002017miR-146a, miR-146b, and miR-155 increase expression of IL-6 and IL-8 and support HSP10 in an In vitro sepsis model.41
290288112017Elevated expression of HSP10 protein inhibits apoptosis and associates with poor prognosis of astrocytoma.11
279935802017High expression of heat shock protein 10 correlates negatively with estrogen/progesterone receptor status and predicts poor prognosis in invasive ductal breast carcinoma.5
286621002017miR-146a, miR-146b, and miR-155 increase expression of IL-6 and IL-8 and support HSP10 in an In vitro sepsis model.41
290288112017Elevated expression of HSP10 protein inhibits apoptosis and associates with poor prognosis of astrocytoma.11
274913022016Quantitative patterns of Hsps in tubular adenoma compared with normal and tumor tissues reveal the value of Hsp10 and Hsp60 in early diagnosis of large bowel cancer.22

Citation

Dessen P

HSPE1 (heat shock protein family E (Hsp10) member 1)

Atlas Genet Cytogenet Oncol Haematol. 2003-08-01

Online version: http://atlasgeneticsoncology.org/gene/40889/hspe1-(heat-shock-protein-family-e-(hsp10)-member-1)