FOXN2 (forkhead box N2)

2003-12-01  

Identity

HGNC
LOCATION
2p16.3
LOCUSID
ALIAS
HTLF
FUSION GENES

Other Information

Locus ID:

NCBI: 3344
MIM: 143089
HGNC: 5281
Ensembl: ENSG00000170802

Variants:

dbSNP: 3344
ClinVar: 3344
TCGA: ENSG00000170802
COSMIC: FOXN2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000170802ENST00000340553P32314
ENSG00000170802ENST00000413569C9JTA7
ENSG00000170802ENST00000616844A0A087X1X6

Expression (GTEx)

0
5
10
15
20
25

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
373187412024Hsa_circ_0001741 Suppresses Ovarian Cancer Cell Proliferations Through Adsorption of miR-188-5p and Promotion of FOXN2 Expression.1
387055652024Bmi1 facilitates the progression of cholangiocarcinoma by inhibiting Foxn2 expression dependent on a histone H2A ubiquitination manner.0
389548052024FOXN2, identified as a novel biomarker in serum, modulates the transforming growth factor-beta signaling pathway through its interaction with partitioning defective 6 homolog alpha, contributing to the pathogenesis of gastric cancer.0
373187412024Hsa_circ_0001741 Suppresses Ovarian Cancer Cell Proliferations Through Adsorption of miR-188-5p and Promotion of FOXN2 Expression.1
387055652024Bmi1 facilitates the progression of cholangiocarcinoma by inhibiting Foxn2 expression dependent on a histone H2A ubiquitination manner.0
389548052024FOXN2, identified as a novel biomarker in serum, modulates the transforming growth factor-beta signaling pathway through its interaction with partitioning defective 6 homolog alpha, contributing to the pathogenesis of gastric cancer.0
335770272021FOXN2 suppresses the proliferation and invasion of human hepatocellular carcinoma cells.6
350084352021HOXC6-Mediated miR-188-5p Expression Induces Cell Migration through the Inhibition of the Tumor Suppressor FOXN2.8
335770272021FOXN2 suppresses the proliferation and invasion of human hepatocellular carcinoma cells.6
350084352021HOXC6-Mediated miR-188-5p Expression Induces Cell Migration through the Inhibition of the Tumor Suppressor FOXN2.8
307201552019Long non-coding RNA WT1-AS inhibits cell aggressiveness via miR-203a-5p/FOXN2 axis and is associated with prognosis in cervical cancer.17
307201552019Long non-coding RNA WT1-AS inhibits cell aggressiveness via miR-203a-5p/FOXN2 axis and is associated with prognosis in cervical cancer.17
293965482018β-Trcp ubiquitin ligase and RSK2 kinase-mediated degradation of FOXN2 promotes tumorigenesis and radioresistance in lung cancer.26
293965482018β-Trcp ubiquitin ligase and RSK2 kinase-mediated degradation of FOXN2 promotes tumorigenesis and radioresistance in lung cancer.26
268020492016Helicase-like transcription factor is a RUNX1 target whose downregulation promotes genomic instability and correlates with complex cytogenetic features in acute myeloid leukemia.8

Citation

Dessen P

FOXN2 (forkhead box N2)

Atlas Genet Cytogenet Oncol Haematol. 2003-12-01

Online version: http://atlasgeneticsoncology.org/gene/40896/foxn2-(forkhead-box-n2)