IBSP (integrin binding sialoprotein)

2003-11-01  

Identity

HGNC
IBSP
LOCATION
4q22.1
LOCUSID
3381
ALIAS
BNSP,BSP,BSP-II,SP-II
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 3381
MIM: 147563
HGNC: 5341
Ensembl: ENSG00000029559

Variants:

dbSNP: 3381
ClinVar: 3381
TCGA: ENSG00000029559
COSMIC: IBSP

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000029559ENST00000226284P21815

Expression (GTEx)

0
1
2
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Focal adhesionKEGGko04510
ECM-receptor interactionKEGGko04512
Focal adhesionKEGGhsa04510
ECM-receptor interactionKEGGhsa04512
PI3K-Akt signaling pathwayKEGGhsa04151
PI3K-Akt signaling pathwayKEGGko04151
Extracellular matrix organizationREACTOMER-HSA-1474244
ECM proteoglycansREACTOMER-HSA-3000178
Integrin cell surface interactionsREACTOMER-HSA-216083

References

Pubmed IDYearTitleCitations
380063952023High expression of integrin-binding sialoprotein (IBSP) is associated with poor prognosis of osteosarcoma.0
380063952023High expression of integrin-binding sialoprotein (IBSP) is associated with poor prognosis of osteosarcoma.0
350812292022Preservation of immunoexpression of type I collagen, BSP and BMP4 in the dentin-pulp complex of head and neck cancer patients after radiotherapy.1
350812292022Preservation of immunoexpression of type I collagen, BSP and BMP4 in the dentin-pulp complex of head and neck cancer patients after radiotherapy.1
339879802021IBSP, a potential recurrence biomarker, promotes the progression of colorectal cancer via Fyn/β-catenin signaling pathway.7
339879802021IBSP, a potential recurrence biomarker, promotes the progression of colorectal cancer via Fyn/β-catenin signaling pathway.7
323023302020Serum levels of bone sialoprotein correlate with portal pressure in patients with liver cirrhosis.2
323626162020Serum levels of bone sialoprotein, osteopontin, and β2-microglobulin in stage I of multiple myeloma.6
323023302020Serum levels of bone sialoprotein correlate with portal pressure in patients with liver cirrhosis.2
323626162020Serum levels of bone sialoprotein, osteopontin, and β2-microglobulin in stage I of multiple myeloma.6
278814742017Cancer Secretome May Influence BSP and DSP Expression in Human Salivary Gland Cells.2
278814742017Cancer Secretome May Influence BSP and DSP Expression in Human Salivary Gland Cells.2
264139772016Preameloblast-Derived Factors Mediate Osteoblast Differentiation of Human Bone Marrow Mesenchymal Stem Cells by Runx2-Osterix-BSP Signaling.1
273231132016Serum levels of PSA, ALP, ICTP, and BSP in prostate cancer patients and the significance of ROC curve in the diagnosis of prostate cancer bone metastases.12
264139772016Preameloblast-Derived Factors Mediate Osteoblast Differentiation of Human Bone Marrow Mesenchymal Stem Cells by Runx2-Osterix-BSP Signaling.1

Citation

Dessen P

IBSP (integrin binding sialoprotein)

Atlas Genet Cytogenet Oncol Haematol. 2003-11-01

Online version: http://atlasgeneticsoncology.org/gene/40908/ibsp-(integrin-binding-sialoprotein)