ICAM3 (intercellular adhesion molecule 3)

2003-11-01  

Identity

HGNC
LOCATION
19p13.2
LOCUSID
ALIAS
CD50,CDW50,ICAM-R
FUSION GENES

Other Information

Locus ID:

NCBI: 3385
MIM: 146631
HGNC: 5346
Ensembl: ENSG00000076662

Variants:

dbSNP: 3385
ClinVar: 3385
TCGA: ENSG00000076662
COSMIC: ICAM3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000076662ENST00000160262P32942
ENSG00000076662ENST00000160262A0A024R7C1
ENSG00000076662ENST00000585439K7EMH0
ENSG00000076662ENST00000589249K7ELH4
ENSG00000076662ENST00000589261K7ERN2
ENSG00000076662ENST00000589580K7ERJ4
ENSG00000076662ENST00000590569K7EQC7
ENSG00000076662ENST00000592439K7EP52
ENSG00000076662ENST00000592945K7ERF0

Expression (GTEx)

0
50
100
150
200
250

Pathways

PathwaySourceExternal ID
Cell adhesion molecules (CAMs)KEGGko04514
Cell adhesion molecules (CAMs)KEGGhsa04514
Immune SystemREACTOMER-HSA-168256
Adaptive Immune SystemREACTOMER-HSA-1280218
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cellREACTOMER-HSA-198933
Innate Immune SystemREACTOMER-HSA-168249
C-type lectin receptors (CLRs)REACTOMER-HSA-5621481
CD209 (DC-SIGN) signalingREACTOMER-HSA-5621575
Extracellular matrix organizationREACTOMER-HSA-1474244
Integrin cell surface interactionsREACTOMER-HSA-216083

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
358493322022Functional evaluation of various ICAM3 transcript variants in diffuse large B-Cell lymphoma.0
358493322022Functional evaluation of various ICAM3 transcript variants in diffuse large B-Cell lymphoma.0
339993582021Association of Circulating ICAM3 Concentrations with Severity and Short-term Outcomes of Acute Ischemic Stroke.0
339993582021Association of Circulating ICAM3 Concentrations with Severity and Short-term Outcomes of Acute Ischemic Stroke.0
320130312020Changes in the Surface Expression of Intercellular Adhesion Molecule 3, the Induction of Apoptosis, and the Inhibition of Cell-Cycle Progression of Human Multidrug-Resistant Jurkat/A4 Cells Exposed to a Random Positioning Machine.8
323714472020Vascular injury biomarkers and stroke risk: A population-based study.5
320130312020Changes in the Surface Expression of Intercellular Adhesion Molecule 3, the Induction of Apoptosis, and the Inhibition of Cell-Cycle Progression of Human Multidrug-Resistant Jurkat/A4 Cells Exposed to a Random Positioning Machine.8
323714472020Vascular injury biomarkers and stroke risk: A population-based study.5
294773782018ICAM3 mediates inflammatory signaling to promote cancer cell stemness.15
296711172018Lewis-antigen-containing ICAM-2/3 on Jurkat leukemia cells interact with DC-SIGN to regulate DC functions.0
297293152018ICAM3 mediates tumor metastasis via a LFA-1-ICAM3-ERM dependent manner.10
294773782018ICAM3 mediates inflammatory signaling to promote cancer cell stemness.15
296711172018Lewis-antigen-containing ICAM-2/3 on Jurkat leukemia cells interact with DC-SIGN to regulate DC functions.0
297293152018ICAM3 mediates tumor metastasis via a LFA-1-ICAM3-ERM dependent manner.10
275523322017Increased Cell Adhesion Molecules, PECAM-1, ICAM-3, or VCAM-1, Predict Increased Risk for Flare in Patients With Quiescent Inflammatory Bowel Disease.13

Citation

Dessen P

ICAM3 (intercellular adhesion molecule 3)

Atlas Genet Cytogenet Oncol Haematol. 2003-11-01

Online version: http://atlasgeneticsoncology.org/gene/40911/icam3