Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3399
MIM: 600277
HGNC: 5362
Ensembl: ENSG00000117318
Variants:
dbSNP: 3399
ClinVar: 3399
TCGA: ENSG00000117318
COSMIC: ID3
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000117318 | ENST00000374561 | Q02535 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37668961 | 2024 | Inhibitor of DNA Binding Protein 3 (ID3) and Nuclear Respiratory Factor 1 (NRF1) Mediated Transcriptional Gene Signatures are Associated with the Severity of Cerebral Amyloid Angiopathy. | 1 |
| 37871574 | 2024 | Tissue-infiltrating alloreactive T cells require Id3 to deflect PD-1-mediated immune suppression during GVHD. | 0 |
| 38244313 | 2024 | ALDOA coordinates PDE3A through the β-catenin/ID3 axis to stimulate cancer metastasis and M2 polarization in lung cancer with EGFR mutations. | 0 |
| 38326607 | 2024 | The nuclear factor ID3 endows macrophages with a potent anti-tumour activity. | 1 |
| 38513475 | 2024 | ID3 is a novel target gene of p53 and modulates lung cancer cell metastasis. | 0 |
| 37668961 | 2024 | Inhibitor of DNA Binding Protein 3 (ID3) and Nuclear Respiratory Factor 1 (NRF1) Mediated Transcriptional Gene Signatures are Associated with the Severity of Cerebral Amyloid Angiopathy. | 1 |
| 37871574 | 2024 | Tissue-infiltrating alloreactive T cells require Id3 to deflect PD-1-mediated immune suppression during GVHD. | 0 |
| 38244313 | 2024 | ALDOA coordinates PDE3A through the β-catenin/ID3 axis to stimulate cancer metastasis and M2 polarization in lung cancer with EGFR mutations. | 0 |
| 38326607 | 2024 | The nuclear factor ID3 endows macrophages with a potent anti-tumour activity. | 1 |
| 38513475 | 2024 | ID3 is a novel target gene of p53 and modulates lung cancer cell metastasis. | 0 |
| 37170184 | 2023 | A positive feedback loop between ID3 and PPARγ via DNA damage repair regulates the efficacy of radiotherapy for rectal cancer. | 0 |
| 38112574 | 2023 | Investigating the ID3/SLC22A4 as immune-related signatures in ischemic stroke. | 0 |
| 37170184 | 2023 | A positive feedback loop between ID3 and PPARγ via DNA damage repair regulates the efficacy of radiotherapy for rectal cancer. | 0 |
| 38112574 | 2023 | Investigating the ID3/SLC22A4 as immune-related signatures in ischemic stroke. | 0 |
| 34877804 | 2022 | Loss of ID3 in pancreatic cancer cells increases DNA damage without impairing MDC1 recruitment to the nuclear foci. | 2 |
Citation
Dessen P
ID3 (inhibitor of DNA binding 3, HLH protein)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/40915/id3
