Identity
HGNC
LOCATION
21q22.11
LOCUSID
ALIAS
IFN-R,IFN-alpha-REC,IFNABR,IFNARB,IMD45
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3455
MIM: 602376
HGNC: 5433
Ensembl: ENSG00000249624
Variants:
dbSNP: 3455
ClinVar: 3455
TCGA: ENSG00000249624
COSMIC: IFNAR2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000249624 | ENST00000432231 | H7C3V1 |
| ENSG00000249624 | ENST00000433395 | H0Y3Z8 |
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36927455 | 2023 | Polymorphism in interferon alpha/beta receptor contributes to glucocorticoid response and outcome of ARDS and COVID-19. | 3 |
| 37028439 | 2023 | Association of IFNAR1 and IFNAR2 with COVID-19 severity. | 3 |
| 36927455 | 2023 | Polymorphism in interferon alpha/beta receptor contributes to glucocorticoid response and outcome of ARDS and COVID-19. | 3 |
| 37028439 | 2023 | Association of IFNAR1 and IFNAR2 with COVID-19 severity. | 3 |
| 34355676 | 2022 | Deleterious single nucleotide polymorphisms (SNPs) of human IFNAR2 gene facilitate COVID-19 severity in patients: a comprehensive in silico approach. | 8 |
| 35081872 | 2022 | Long non-coding RNA prostate cancer-associated transcript 6 inhibited gefitinib sensitivity of non-small cell lung cancer by serving as a competing endogenous RNA of miR-326 to up-regulate interferon-alpha receptor 2. | 8 |
| 35442417 | 2022 | Life-threatening viral disease in a novel form of autosomal recessive IFNAR2 deficiency in the Arctic. | 26 |
| 35967349 | 2022 | IFNAR2 relevance in the clinical outcome of individuals with severe COVID-19. | 14 |
| 36439115 | 2022 | Type I interferon receptor (IFNAR2) deficiency reveals Zika virus cytopathicity in human macrophages and microglia. | 1 |
| 36672770 | 2022 | Polymorphisms in ACE1, TMPRSS2, IFIH1, IFNAR2, and TYK2 Genes Are Associated with Worse Clinical Outcomes in COVID-19. | 12 |
| 34355676 | 2022 | Deleterious single nucleotide polymorphisms (SNPs) of human IFNAR2 gene facilitate COVID-19 severity in patients: a comprehensive in silico approach. | 8 |
| 35081872 | 2022 | Long non-coding RNA prostate cancer-associated transcript 6 inhibited gefitinib sensitivity of non-small cell lung cancer by serving as a competing endogenous RNA of miR-326 to up-regulate interferon-alpha receptor 2. | 8 |
| 35442417 | 2022 | Life-threatening viral disease in a novel form of autosomal recessive IFNAR2 deficiency in the Arctic. | 26 |
| 35967349 | 2022 | IFNAR2 relevance in the clinical outcome of individuals with severe COVID-19. | 14 |
| 36439115 | 2022 | Type I interferon receptor (IFNAR2) deficiency reveals Zika virus cytopathicity in human macrophages and microglia. | 1 |
Citation
Dessen P
IFNAR2 (interferon alpha and beta receptor subunit 2)
Atlas Genet Cytogenet Oncol Haematol. 2003-11-01
Online version: http://atlasgeneticsoncology.org/gene/40923/ifnar2-(interferon-alpha-and-beta-receptor-subunit-2)
