Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3485
MIM: 146731
HGNC: 5471
Ensembl: ENSG00000115457
Variants:
dbSNP: 3485
ClinVar: 3485
TCGA: ENSG00000115457
COSMIC: IGFBP2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000115457 | ENST00000233809 | P18065 |
| ENSG00000115457 | ENST00000434997 | C9JW52 |
| ENSG00000115457 | ENST00000436812 | H7C1H0 |
| ENSG00000115457 | ENST00000456764 | C9JMY1 |
Expression (GTEx)
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37982173 | 2024 | Cancer-associated fibroblast-associated gene IGFBP2 promotes glioma progression through induction of M2 macrophage polarization. | 0 |
| 37992295 | 2024 | Insulin-like growth factor binding protein-2 in at-risk adults and autopsy-confirmed Alzheimer brains. | 1 |
| 38316422 | 2024 | Role of increased IGFBP2 in trophoblast cell proliferation and recurrent spontaneous abortion development: A pilot study. | 1 |
| 38490505 | 2024 | Exosomal IGFBP2 derived from highly metastatic promotes hepatocellular carcinoma metastasis by inducing epithelial mesenchymal transition. | 1 |
| 38506034 | 2024 | The role of HMGA2 in activating the IGFBP2 expression to promote angiogenesis and LUAD metastasis via the PI3K/AKT/VEGFA signaling pathway. | 0 |
| 38729152 | 2024 | A human omentum-specific mesothelial-like stromal population inhibits adipogenesis through IGFBP2 secretion. | 0 |
| 38918360 | 2024 | IGFBP2/ITGA5 promotes gefitinib resistance via activating STAT3/CXCL1 axis in non-small cell lung cancer. | 0 |
| 37982173 | 2024 | Cancer-associated fibroblast-associated gene IGFBP2 promotes glioma progression through induction of M2 macrophage polarization. | 0 |
| 37992295 | 2024 | Insulin-like growth factor binding protein-2 in at-risk adults and autopsy-confirmed Alzheimer brains. | 1 |
| 38316422 | 2024 | Role of increased IGFBP2 in trophoblast cell proliferation and recurrent spontaneous abortion development: A pilot study. | 1 |
| 38490505 | 2024 | Exosomal IGFBP2 derived from highly metastatic promotes hepatocellular carcinoma metastasis by inducing epithelial mesenchymal transition. | 1 |
| 38506034 | 2024 | The role of HMGA2 in activating the IGFBP2 expression to promote angiogenesis and LUAD metastasis via the PI3K/AKT/VEGFA signaling pathway. | 0 |
| 38729152 | 2024 | A human omentum-specific mesothelial-like stromal population inhibits adipogenesis through IGFBP2 secretion. | 0 |
| 38918360 | 2024 | IGFBP2/ITGA5 promotes gefitinib resistance via activating STAT3/CXCL1 axis in non-small cell lung cancer. | 0 |
| 36787736 | 2023 | Loss of IGFBP2 mediates alveolar type 2 cell senescence and promotes lung fibrosis. | 12 |
Citation
Dessen P
IGFBP2 (insulin like growth factor binding protein 2)
Atlas Genet Cytogenet Oncol Haematol. 2003-08-01
Online version: http://atlasgeneticsoncology.org/gene/40931/igfbp2-(insulin-like-growth-factor-binding-protein-2)
