Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3592
MIM: 161560
HGNC: 5969
Ensembl: ENSG00000168811
Variants:
dbSNP: 3592
ClinVar: 3592
TCGA: ENSG00000168811
COSMIC: IL12A
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000168811 | ENST00000305579 | P29459 |
| ENSG00000168811 | ENST00000305579 | O60595 |
| ENSG00000168811 | ENST00000466512 | E9PGR3 |
| ENSG00000168811 | ENST00000480787 | E7ENE1 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA165817016 | Kidney Transplantation | Disease | ClinicalAnnotation | associated | PD | 21107304 | |
| PA166048654 | ustekinumab | Chemical | LabelAnnotation | associated | |||
| PA450566 | mycophenolate mofetil | Chemical | ClinicalAnnotation | associated | PD | 21107304 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38278031 | 2024 | Signaling pathways underlying TGF-β mediated suppression of IL-12A gene expression in monocytes. | 1 |
| 38690286 | 2024 | The effects of IL-27 and IL-35 gene variation and expression levels on the susceptibility and clinical manifestations of pulmonary tuberculosis. | 0 |
| 38278031 | 2024 | Signaling pathways underlying TGF-β mediated suppression of IL-12A gene expression in monocytes. | 1 |
| 38690286 | 2024 | The effects of IL-27 and IL-35 gene variation and expression levels on the susceptibility and clinical manifestations of pulmonary tuberculosis. | 0 |
| 35959714 | 2023 | Immunomodulatory effect of IL-35 gene-transfected mesenchymal stem cells on allergic asthma. | 4 |
| 37195820 | 2023 | A Meta-Analysis of the Association Between Genetic Polymorphisms in IL-12, IL-17, and IL-21 and Risk of Hepatitis B Virus Infection. | 0 |
| 37326977 | 2023 | IL-8 and IL-12p70 are associated with pelvic pain among infertile women with endometriosis. | 1 |
| 37878703 | 2023 | Human interleukin-12α and EBI3 are cytokines with anti-inflammatory functions. | 2 |
| 38203575 | 2023 | Altered Gene Expression of IL-35 and IL-36α in the Skin of Patients with Atopic Dermatitis. | 1 |
| 35959714 | 2023 | Immunomodulatory effect of IL-35 gene-transfected mesenchymal stem cells on allergic asthma. | 4 |
| 37195820 | 2023 | A Meta-Analysis of the Association Between Genetic Polymorphisms in IL-12, IL-17, and IL-21 and Risk of Hepatitis B Virus Infection. | 0 |
| 37326977 | 2023 | IL-8 and IL-12p70 are associated with pelvic pain among infertile women with endometriosis. | 1 |
| 37878703 | 2023 | Human interleukin-12α and EBI3 are cytokines with anti-inflammatory functions. | 2 |
| 38203575 | 2023 | Altered Gene Expression of IL-35 and IL-36α in the Skin of Patients with Atopic Dermatitis. | 1 |
| 33878182 | 2022 | Altered CD4+ T cell and cytokine levels in peripheral blood and skin samples from systemic sclerosis patients and IL-35 in CD4+ T cell growth. | 8 |
Citation
Dessen P
IL12A (interleukin 12A)
Atlas Genet Cytogenet Oncol Haematol. 2003-08-01
Online version: http://atlasgeneticsoncology.org/gene/40940/il12a-(interleukin-12a)
