Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 59067
MIM: 605384
HGNC: 6005
Ensembl: ENSG00000138684
Variants:
dbSNP: 59067
ClinVar: 59067
TCGA: ENSG00000138684
COSMIC: IL21
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000138684 | ENST00000611104 | Q9HBE4 |
| ENSG00000138684 | ENST00000648588 | Q9HBE4 |
| ENSG00000138684 | ENST00000648588 | A0A224B028 |
Expression (GTEx)
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37972478 | 2024 | The role of Interleukin-21 in autoimmune Diseases: Mechanisms, therapeutic Implications, and future directions. | 1 |
| 38638431 | 2024 | Therapeutic potential of interleukin-21 in cancer. | 0 |
| 37972478 | 2024 | The role of Interleukin-21 in autoimmune Diseases: Mechanisms, therapeutic Implications, and future directions. | 1 |
| 38638431 | 2024 | Therapeutic potential of interleukin-21 in cancer. | 0 |
| 36738539 | 2023 | Characterization of peripheral blood T follicular helper (TFH) cells in patients with type 1 Gaucher disease and carriers. | 0 |
| 36872451 | 2023 | IL-21 boosts germinal center response through independent actions on T and B cells in a concentration-dependent manner. | 1 |
| 37107636 | 2023 | IL-21 (rs2055979 and rs2221903)/IL-21R (rs3093301) Polymorphism and High Levels of IL-21 Are Associated with Rheumatoid Arthritis in Mexican Patients. | 2 |
| 37195820 | 2023 | A Meta-Analysis of the Association Between Genetic Polymorphisms in IL-12, IL-17, and IL-21 and Risk of Hepatitis B Virus Infection. | 0 |
| 37196065 | 2023 | Clonally expanded, thyrotoxic effector CD8(+) T cells driven by IL-21 contribute to checkpoint inhibitor thyroiditis. | 6 |
| 37220805 | 2023 | Interleukin-21 promotes Type-1 activation and cytotoxicity of CD56(dim)CD16(bright) natural killer cells during kidney allograft antibody-mediated rejection showing a new link between adaptive and innate humoral allo-immunity. | 3 |
| 37249661 | 2023 | Implications of IL-21 in solid tumor therapy. | 3 |
| 37339051 | 2023 | A structural blueprint for interleukin-21 signal modulation. | 0 |
| 37415982 | 2023 | Evaluation of plasma IL-21 as a potential biomarker for type 1 diabetes progression. | 0 |
| 37628716 | 2023 | T Follicular Helper Cells in Tertiary Lymphoid Structure Contribute to Renal Fibrosis by IL-21. | 1 |
| 37759505 | 2023 | Interleukin-21 Influences Glioblastoma Course: Biological Mechanisms and Therapeutic Potential. | 1 |
Citation
Dessen P
IL21 (interleukin 21)
Atlas Genet Cytogenet Oncol Haematol. 2003-05-01
Online version: http://atlasgeneticsoncology.org/gene/40954/il21
