Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3559
MIM: 147730
HGNC: 6008
Ensembl: ENSG00000134460
Variants:
dbSNP: 3559
ClinVar: 3559
TCGA: ENSG00000134460
COSMIC: IL2RA
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000134460 | ENST00000256876 | Q5W006 |
| ENSG00000134460 | ENST00000379954 | Q5W005 |
| ENSG00000134460 | ENST00000379959 | P01589 |
| ENSG00000134460 | ENST00000447847 | H0Y5Z0 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA164750594 | denileukin diftitox | Chemical | LabelAnnotation | associated |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37843874 | 2024 | IL2RA rs2104286 and IL2 rs2069762 polymorphisms may be associated with bipolar disorder and its clinical findings. | 0 |
| 38037265 | 2024 | The soluble IL-2 receptor α/CD25 as a modulator of IL-2 function. | 1 |
| 38195135 | 2024 | Evaluation of gene-gene interaction between the interleukin (IL)-2 and IL-2RA gene polymorphisms in schizophrenia patients in the Turkish Population. | 0 |
| 38394507 | 2024 | Interleukin gene polymorphisms and alopecia areata: A systematic review and meta-analysis. | 0 |
| 38805281 | 2024 | Long noncoding RNA LIRIL2R modulates FOXP3 levels and suppressive function of human CD4(+) regulatory T cells by regulating IL2RA. | 1 |
| 37843874 | 2024 | IL2RA rs2104286 and IL2 rs2069762 polymorphisms may be associated with bipolar disorder and its clinical findings. | 0 |
| 38037265 | 2024 | The soluble IL-2 receptor α/CD25 as a modulator of IL-2 function. | 1 |
| 38195135 | 2024 | Evaluation of gene-gene interaction between the interleukin (IL)-2 and IL-2RA gene polymorphisms in schizophrenia patients in the Turkish Population. | 0 |
| 38394507 | 2024 | Interleukin gene polymorphisms and alopecia areata: A systematic review and meta-analysis. | 0 |
| 38805281 | 2024 | Long noncoding RNA LIRIL2R modulates FOXP3 levels and suppressive function of human CD4(+) regulatory T cells by regulating IL2RA. | 1 |
| 37169554 | 2023 | CD4+CD25+CD127(lo)FOXP3+ cell in food allergy: Does it predict anaphylaxis? | 0 |
| 37724526 | 2023 | DNA methylation differences within INS, PTPN22 and IL2RA promoters in lymphocyte subsets in children with type 1 diabetes and controls. | 0 |
| 37169554 | 2023 | CD4+CD25+CD127(lo)FOXP3+ cell in food allergy: Does it predict anaphylaxis? | 0 |
| 37724526 | 2023 | DNA methylation differences within INS, PTPN22 and IL2RA promoters in lymphocyte subsets in children with type 1 diabetes and controls. | 0 |
| 34724091 | 2022 | Prognostic value of preoperative soluble interleukin 2 receptor α as a novel immune biomarker in epithelial ovarian cancer. | 2 |
Citation
Dessen P
IL2RA (interleukin 2 receptor subunit alpha)
Atlas Genet Cytogenet Oncol Haematol. 2003-08-01
Online version: http://atlasgeneticsoncology.org/gene/40957/il2ra-(interleukin-2-receptor-subunit-alpha)
