IL9 (interleukin 9)

2003-06-01  

Identity

HGNC
IL9
LOCATION
5q31.1
LOCUSID
3578
ALIAS
HP40,IL-9,P40
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 3578
MIM: 146931
HGNC: 6029
Ensembl: ENSG00000145839

Variants:

dbSNP: 3578
ClinVar: 3578
TCGA: ENSG00000145839
COSMIC: IL9

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000145839ENST00000274520P15248

Expression (GTEx)

0
1
2
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Cytokine-cytokine receptor interactionKEGGko04060
Jak-STAT signaling pathwayKEGGko04630
AsthmaKEGGko05310
Cytokine-cytokine receptor interactionKEGGhsa04060
Jak-STAT signaling pathwayKEGGhsa04630
AsthmaKEGGhsa05310
Immune SystemREACTOMER-HSA-168256
Cytokine Signaling in Immune systemREACTOMER-HSA-1280215
Signaling by InterleukinsREACTOMER-HSA-449147

References

Pubmed IDYearTitleCitations
206744012010Interferon-regulatory factor 4 is essential for the developmental program of T helper 9 cells.180
227724642012Robust tumor immunity to melanoma mediated by interleukin-9-producing T cells.131
177034122007Genetic susceptibility to respiratory syncytial virus bronchiolitis is predominantly associated with innate immune genes.100
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.85
242164822013Th9 cell development requires a BATF-regulated transcriptional network.65
233760582013Interleukin-9 is required for allergic airway inflammation mediated by the cytokine TSLP.63
204983572010TGF-beta induces IL-9 production from human Th17 cells.52
249572652015IL-9 and its receptor are predominantly involved in the pathogenesis of UC.51
127892352003Segmental allergen challenge in patients with atopic asthma leads to increased IL-9 expression in bronchoalveolar lavage fluid lymphocytes.38
156217232004IL-9 and its receptor: from signal transduction to tumorigenesis.36

Citation

Dessen P

IL9 (interleukin 9)

Atlas Genet Cytogenet Oncol Haematol. 2003-06-01

Online version: http://atlasgeneticsoncology.org/gene/40968/il9-(interleukin-9)